Agati, G., Azzarello, E., Pollastri, S., & Tattini, M. (2012). Flavonoids as antioxidants in plants: location and functional significance. Plant Science, 196, 67-76. https://doi.org/10.1016/j.plantsci.2012.07.014
Ageorges, A., Fernandez, L., Vialet, S., Merdinoglu, D., Terrier, N., and Romieu, C. (2006). Four specific isogenes of the anthocyanin metabolic pathway are systematically co-expressed with the red colour of grape berries. Plant Science 170(2), 372-383. doi: 10.1016/j.plantsci.2005.09.007.
Allan, A.C., and Espley, R.V. (2018). MYBs Drive Novel Consumer Traits in Fruits and Vegetables. Trends Plant Sci 23(8), 693-705. doi: 10.1016/j.tplants.2018.06.001.
An, J.P., Wang, X.F., Li, Y.Y., Song, L.Q., Zhao, L.L., You, C.X., et al. (2018). EIN3-LIKE1, MYB1, and ETHYLENE RESPONSE FACTOR3 Act in a Regulatory Loop That Synergistically Modulates Ethylene Biosynthesis and Anthocyanin Accumulation. Plant Physiology 178(2), 808-823. doi: 10.1104/pp.18.00068.
An, J.P., Zhang, X.W., Bi, S.Q., You, C.X., Wang, X.F., and Hao, Y.J. (2020). The ERF transcription factor MdERF38 promotes drought stress-induced anthocyanin biosynthesis in apple. Plant J 101(3), 573-589. doi: 10.1111/tpj.14555.
Azuma, A., Kobayashi, S., Mitani, N., Shiraishi, M., Yamada, M., Ueno, T., et al. (2008). Genomic and genetic analysis of Myb-related genes that regulate anthocyanin biosynthesis in grape berry skin. Theor Appl Genet 117(6), 1009-1019. doi: 10.1007/s00122-008-0840-1.
Bai, S., Tao, R., Tang, Y., Yin, L., Ma, Y., Ni, J., et al. (2019). BBX16, a B-box protein, positively regulates light-induced anthocyanin accumulation by activating MYB10 in red pear. Plant Biotechnol J 17(10), 1985-19 97. doi: 10.1111/pbi.13114.
Bogs, J., Jaffe, F.W., Takos, A.M., Walker, A.R., and Robinson, S.P. (2007). The grapevine transcription factor VvMYBPA1 regulates proanthocyanidin synthesis during fruit development. Plant Physiol 143(3), 1347-1361. doi: 10.1104/pp.106.093203.
Boss, P.K., Davies, C., and Robinson, S.P. (1996). Expression of anthocyanin biosynthesis pathway genes in red and white grapes. Plant Molecular Biology 32(3), 565-569. doi: 10.1007/bf00019111.
Canaguier, A., Grimplet, J., Di Gaspero, G., Scalabrin, S., Duchene, E., Choisne, N., et al. (2017). A new version of the grapevine reference genome assembly (12X.v2) and of its annotation (VCost.v3). Genom Data 14, 56-62. doi: 10.1016/j.gdata.2017.09.002.
Cavallini, E., Matus, J.T., Finezzo, L., Zenoni, S., Loyola, R., Guzzo, F., et al. (2015). The phenylpropanoid pathway is controlled at different branches by a set of R2R3-MYB C2 repressors in grapevine. Plant Physiol 167(4), 1448-1470. doi: 10.1104/pp.114.256172.
Chen, W.K., Wang, Y., Gao, X.T., Yang, X.H., He, F., Duan, C.Q., et al. (2018). Flavonoid and aromatic profiles of two Vitis vinifera L. teinturier grape cultivars. Australian Journal of Grape and Wine Research 24(3), 379-389. doi: 10.1111/ajgw.12336.
Coombe, B. G., & Bishop, G. R. (1980). Development of the grape berry. II. Changes in diameter and deformability during veraison. Australian Journal of Agricultural Research, 31(3), 499-509. https://doi.org/10.1071/AR9800499
Cui, Y., Zhai, Y., Flaishman, M., Li, J., Chen, S., Zheng, C., et al. (2021). Ethephon induces coordinated ripening acceleration and divergent coloration responses in fig (Ficus carica L.) flowers and receptacles. Plant Mol Biol 105(4-5), 347-364. doi: 10.1007/s11103-020-01092-x.
Czemmel, S., Stracke, R., Weisshaar, B., Cordon, N., Harris, N.N., Walker, A.R., et al. (2009). The grapevine R2R3-MYB transcription factor VvMYBF1 regulates flavonol synthesis in developing grape berries. Plant Physiol 151(3), 1513-1530. doi: 10.1104/pp.109.142059.
Dalman, K., Wind, J.J., Nemesio-Gorriz, M., Hammerbacher, A., Lunden, K., Ezcurra, I., et al. (2017). Overexpression of PaNAC03, a stress induced NAC gene family transcription factor in Norway spruce leads to reduced flavonol biosynthesis and aberrant embryo development. BMC Plant Biol 17(1), 6. doi: 10.1186/s12870-016-0952-8.
Dixon, D.P., and Edwards, R. (2010). Roles for stress-inducible lambda glutathione transferases in flavonoid metabolism in plants as identified by ligand fishing. J Biol Chem 285(47), 36322-36329. doi: 10.1074/jbc.M110.164806.
Dombrecht, B., Xue, G.P., Sprague, S.J., Kirkegaard, J.A., Ross, J.J., Reid, J.B., et al. (2007). MYC2 differentially modulates diverse jasmonate-dependent functions in Arabidopsis. Plant Cell 19(7), 2225-2245. doi: 10.1105/tpc.106.048017.
Dubos, C., Stracke, R., Grotewold, E., Weisshaar, B., Martin, C., and Lepiniec, L. (2010). MYB transcription factors in Arabidopsis. Trends Plant Sci 15(10), 573-581. doi: 10.1016/j.tplants.2010.06.005.
Fuleki, T., and Ricardo-da-Silva, J.M. (1997). Catechin and procyanidin composition of seeds from grape cultivars grown in Ontario. Journal of Agricultural and Food Chemistry 45(4), 1156-1160. doi: 10.1021/jf960493k.
Fursova, O.V., Pogorelko, G.V., and Tarasov, V.A. (2009). Identification of ICE2, a gene involved in cold acclimation which determines freezing tolerance in Arabidopsis thaliana. Gene 429(1-2), 98-103. doi: 10.1016/j.gene.2008.10.016.
He, J.J., Liu, Y.X., Pan, Q.H., Cui, X.Y., and Duan, C.Q. (2010). Different anthocyanin profiles of the skin and the pulp of Yan7 (Muscat Hamburg x Alicante Bouschet) grape berries. Molecules 15(3), 1141-1153. doi: 10.3390/molecules15031141.
Henry-Kirk, R.A., Plunkett, B., Hall, M., McGhie, T., Allan, A.C., Wargent, J.J., et al. (2018). Solar UV light regulates flavonoid metabolism in apple (Malus x domestica). Plant Cell Environ 41(3), 675-688. doi: 10.1111/pce.13125.
Hichri, I., Heppel, S.C., Pillet, J., Leon, C., Czemmel, S., Delrot, S., et al. (2010). The basic helix-loop-helix transcription factor MYC1 is involved in the regulation of the flavonoid biosynthesis pathway in grapevine. Mol Plant 3(3), 509-523. doi: 10.1093/mp/ssp118.
Jaakola, L. (2013). New insights into the regulation of anthocyanin biosynthesis in fruits. Trends in Plant Science 18(9): 477-483.
Jaakola, L., Poole, M., Jones, M.O., Kamarainen-Karppinen, T., Koskimaki, J.J., Hohtola, A., et al. (2010). A SQUAMOSA MADS box gene involved in the regulation of anthocyanin accumulation in bilberry fruits. Plant Physiol 153(4), 1619-1629. doi: 10.1104/pp.110.158279.
Jeong, S.T., Goto-Yamamoto, N., Hashizume, K., and Esaka, M. (2006). Expression of the flavonoid 3′-hydroxylase and flavonoid 3′,5′-hydroxylase genes and flavonoid composition in grape (Vitis vinifera). Plant Science 170(1), 61-69. doi: 10.1016/j.plantsci.2005.07.025.
Jiu, S., Guan, L., Leng, X., Zhang, K., Haider, M.S., Yu, X., et al. (2021). The role of VvMYBA2r and VvMYBA2w alleles of the MYBA2 locus in the regulation of anthocyanin biosynthesis for molecular breeding of grape (Vitis spp.) skin coloration. Plant Biotechnol J. doi: 10.1111/pbi.13543.
Kim, D., Langmead, B., and Salzberg, S.L. (2015). HISAT: a fast spliced aligner with low memory requirements. Nature Methods 12(4), 357-U121. doi: 10.1038/nmeth.3317.
Kobayashi, S. (2004). Retrotransposon-Induced Mutations in Grape Skin Color. Science 304(5673), 982-982. doi: 10.1126/science.1095011.
Koyama, K., Numata, M., Nakajima, I., Goto-Yamamoto, N., Matsumura, H., and Tanaka, N. (2014). Functional characterization of a new grapevine MYB transcription factor and regulation of proanthocyanidin biosynthesis in grapes. J Exp Bot 65(15), 4433-4449. doi: 10.1093/jxb/eru213.
Koyama, T., and Sato, F. (2018). The function of ETHYLENE RESPONSE FACTOR genes in the light-induced anthocyanin production of Arabidopsis thaliana leaves. Plant Biotechnology 35(1), 87-91. doi: 10.5511/plantbiotechnology.18.0122b.
Kuang, L., Chen, S., Guo, Y., and Ma, H. (2019). Quantitative Proteome Analysis Reveals Changes in the Protein Landscape During Grape Berry Development With a Focus on Vacuolar Transport Proteins. Front Plant Sci 10, 641. doi: 10.3389/fpls.2019.00641.
LaFountain, A.M., and Yuan, Y.W. (2021). Repressors of anthocyanin biosynthesis. New Phytol 231(3), 933-949. doi: 10.1111/nph.17397.
Leng, F., Cao, J., Ge, Z., Wang, Y., Zhao, C., Wang, S., et al. (2020). Transcriptomic Analysis of Root Restriction Effects on Phenolic Metabolites during Grape Berry Development and Ripening. J Agric Food Chem 68(34), 9090-9099. doi: 10.1021/acs.jafc.0c02488.
Li, Y.Y., Mao, K., Zhao, C., Zhao, X.Y., Zhang, H.L., Shu, H.R., et al. (2012). MdCOP1 ubiquitin E3 ligases interact with MdMYB1 to regulate light-induced anthocyanin biosynthesis and red fruit coloration in apple. Plant Physiol 160(2), 1011-1022. doi: 10.1104/pp.112.199703.
Lu, S., Wang, J., Zhuge, Y., Zhang, M., Liu, C., Jia, H., et al. (2021). Integrative Analyses of Metabolomes and Transcriptomes Provide Insights into Flavonoid Variation in Grape Berries. J Agric Food Chem. doi: 10.1021/acs.jafc.1c02703.
Maier, A., Schrader, A., Kokkelink, L., Falke, C., Welter, B., Iniesto, E., et al. (2013). Light and the E3 ubiquitin ligase COP1/SPA control the protein stability of the MYB transcription factors PAP1 and PAP2 involved in anthocyanin accumulation in Arabidopsis. Plant J 74(4), 638-651. doi: 10.1111/tpj.12153.
Malacarne, G., Coller, E., Czemmel, S., Vrhovsek, U., Engelen, K., Goremykin, V., et al. (2016). The grapevine VvibZIPC22 transcription factor is involved in the regulation of flavonoid biosynthesis. J Exp Bot 67(11), 3509-3522. doi: 10.1093/jxb/erw181.
Ni, J., Premathilake, A.T., Gao, Y., Yu, W., Tao, R., Teng, Y., et al. (2020a). Ethylene-activated PpERF105 induces the expression of the repressor-type R2R3-MYB gene PpMYB140 to inhibit anthocyanin biosynthesis in red pear fruit. Plant J. doi: 10.1111/tpj.15049.
Ni, J., Zhao, Y., Tao, R., Yin, L., Gao, L., Strid, A., et al. (2020b). Ethylene mediates the branching of the jasmonate-induced flavonoid biosynthesis pathway by suppressing anthocyanin biosynthesis in red Chinese pear fruits. Plant Biotechnol J 18(5), 1223-1240. doi: 10.1111/pbi.13287.
Perez-Diaz, R., Ryngajllo, M., Perez-Diaz, J., Pena-Cortes, H., Casaretto, J.A., Gonzalez-Villanueva, E., et al. (2014). VvMATE1 and VvMATE2 encode putative proanthocyanidin transporters expressed during berry development in Vitis vinifera L. Plant Cell Rep 33(7), 1147-1159. doi: 10.1007/s00299-014-1604-9.
Petrussa, E., Braidot, E., Zancani, M., Peresson, C., Bertolini, A., Patui, S., et al. (2013). Plant flavonoids--biosynthesis, transport and involvement in stress responses. Int J Mol Sci 14(7), 14950-14973. doi: 10.3390/ijms140714950.
Robinson, S.P., Pezhmanmehr, M., Speirs, J., McDavid, D.A.J., Hooper, L.C., Rinaldo, A.R., et al. (2019). Grape and wine flavonoid composition in transgenic grapevines with altered expression of flavonoid hydroxylase genes. Australian Journal of Grape and Wine Research 25(3), 293-306. doi: 10.1111/ajgw.12393.
Varet, H., Brillet-Gueguen, L., Coppee, J.-Y., and Dillies, M.-A. (2016). SARTools: A DESeq2-and EdgeR-Based R Pipeline for Comprehensive Differential Analysis of RNA-Seq Data. Plos One 11(6). doi: 10.1371/journal.pone.0157022.
Walker, A.R., Lee, E., Bogs, J., McDavid, D.A., Thomas, M.R., and Robinson, S.P. (2007). White grapes arose through the mutation of two similar and adjacent regulatory genes. Plant J 49(5), 772-785. doi: 10.1111/j.1365-313X.2006.02997.x.
Wang, H., Wang, W., Li, H., Zhang, P., Zhan, J., and Huang, W. (2011). Expression and tissue and subcellular localization of anthocyanidin synthase (ANS) in grapevine. Protoplasma 248(2), 267-279. doi: 10.1007/s00709-010-0160-6.
Wang, Z., Song, M., Wang, Z., Chen, S., and Ma, H. (2021). Metabolome and transcriptome analysis of flavor components and flavonoid biosynthesis in fig female flower tissues (Ficus carica L.) after bagging. BMC Plant Biol 21(1), 396. doi: 10.1186/s12870-021-03169-1.
Xi, H., He, Y., and Chen, H. (2021). Functional Characterization of SmbHLH13 in Anthocyanin Biosynthesis and Flowering in Eggplant. Horticultural Plant Journal 7(1), 73-80. doi: 10.1016/j.hpj.2020.08.006.
Xi, Z.M., Meng, J.F., Huo, S.S., Luan, L.Y., Ma, L.N., and Zhang, Z.W. (2013). Exogenously applied abscisic acid to Yan73 (V. vinifera) grapes enhances phenolic content and antioxidant capacity of its wine. Int J Food Sci Nutr 64(4), 444-451. doi: 10.3109/09637486.2012.746291.
Xie, D.Y., Jackson, L.A., Cooper, J.D., Ferreira, D., and Paiva, N.L. (2004). Molecular and biochemical analysis of two cDNA clones encoding dihydroflavonol-4-reductase from medicago truncatula. Plant Physiology 134(3), 979-994. doi: 10.1104/pp.103.030221.
Xie, S., Qiao, X., Chen, H., Nan, H., and Zhang, Z. (2019). Coordinated Regulation of Grape Berry Flesh Color by Transcriptional Activators and Repressors. J Agric Food Chem 67(42), 11815-11824. doi: 10.1021/acs.jafc.9b05234.
Xie, S., Song, C., Wang, X., Liu, M., Zhang, Z., and Xi, Z. (2015). Tissue-Specific Expression Analysis of Anthocyanin Biosynthetic Genes in White- and Red-Fleshed Grape Cultivars. Molecules 20(12), 22767-22780. doi: 10.3390/molecules201219883.
Xie, S., Zhao, T., Zhang, Z., and Meng, J. (2018). Reduction of Dihydrokaempferol by Vitis vinfera Dihydroflavonol 4-Reductase to Produce Orange Pelargonidin-Type Anthocyanins. J Agric Food Chem 66(13), 3524-3532. doi: 10.1021/acs.jafc.7b05766.
Yang, B., Wei, Y., Liang, C., Guo, J., Niu, T., Zhang, P., et al. (2021). VvANR silencing promotes expression of VvANS and accumulation of anthocyanin in grape berries. Protoplasma. doi: 10.1007/s00709-021-01698-y.
Zhang, J., Xu, H., Wang, N., Jiang, S., Fang, H., Zhang, Z., et al. (2018a). The ethylene response factor MdERF1B regulates anthocyanin and proanthocyanidin biosynthesis in apple. Plant Molecular Biology 98(3), 205-218. doi: 10.1007/s11103-018-0770-5.
Zhang K, Liu Z, Guan L, et al., 2018. Changes of Anthocyanin Component Biosynthesis in 'Summer Black' Grape Berries after the Red Flesh Mutation Occurred. J Agric Food Chem 66, 9209-18.
Zhao, J. (2015). Flavonoid transport mechanisms: how to go, and with whom. Trends Plant Sci 20(9), 576-585. doi: 10.1016/j.tplants.2015.06.007.
Zhao, R., Song, X., Yang, N., Chen, L., Xiang, L., Liu, X.Q., et al. (2020). Expression of the subgroup IIIf bHLH transcription factor CpbHLH1 from Chimonanthus praecox (L.) in transgenic model plants inhibits anthocyanin accumulation. Plant Cell Rep 39(7), 891-907. doi: 10.1007/s00299-020-02537-9.