We investigate a high sensitive chiral molecule detector based on Goos-Hanchen shift (S) in Kretschmann configuration involving chiral TDBCs. Fresnel equations and the stationary phase method are employed to calculate S. Due to the interaction between surface plasmon polaritons and chiral TDBCs, S with chiral TDBCs are amplified at near the resonant wavelengths of chiral TDBCs. Our calculation results show that although the difference between the resonant wavelengths of left and right TDBCs is 4.5nm, the difference of S with chiral TDBCs (ΔS) can reach to 400 times as the incident wavelength in certain conditions, which can be easily observed in experiments. There is an optimal thickness of the metal film to realize the largest difference of S between Kretschmann configurations with left TDBCs and right TDBCs. We also find that the positions of the largest S for the structures with left TDBCs and right TDBCs do not overlap. Furthermore, we discuss the oscillator strength f, which is mainly determined by TDBC concentration. We find that our proposed detector is quite sensitive with f. By changing f from 0.008 to 0.014 with the step of 0.002, the change of ΔS is no less than 5 times of the incident wavelength (2.9μm). Our proposed structure is very sensitive and has potential applications in experiments.