Background: Both percutaneous transhepatic gallbladder drainage (PTGD) and percutaneous transhepatic cholangial drainage(PTCD) can reduce jaundice in patients with obstructive jaundice, and recover of liver function. However, is there difference in effectiveness. No studies have confirmed that. We retrospectively investigated the change rate of jaundice and transaminase change rate in patients underwent PTCD and PTGD surgery. The incidence of complications was also studied.
Methods: Retrospective analysis 106 patients with obstructive jaundice admitted to the First Hospital of Jilin University. 55 patients were treated with PTGD. 51 patients were treated with PTCD. Compared the serum TBil(total bilirubin), DBil(direct bilirubin), IBil(indirect bilirubin), ALT(alanine aminotransferase), AST(aspartate aminotransferase) levels 1 day before and 7 days after surgery, the decrease rate of jaundice was obtained. And compare the incidence of postoperative complications, such as infection, bleeding, and bile leakage, etc.
Results: Reduction was observed in most patients, but elevation was still observed in a few patients. The change rate of jaundice and aminotransferase of PTGD and PTCD group have no significant difference (P>0.05), the incidence of complications have no significant difference between the two groups(P>0.05) .
Conclusions: There was no significant difference between PTGD and PTCD in treatment of obstructive jaundice and incidence of postoperative complications. The appropriate puncture method can be selected according to the specific situation of the patient.