Ethics approval: The Ethical Community of the Military Medical Academy (Belgrade, Serbia): license no. 323-07-00622/2017-05, following the principles of the governmental policy of Official Gazette Republic of Serbia (No. 14/2009) and Directive 2010/63/EU.
Availability of data and materials: The authors confirm that the data supporting the findings of this study are available within the article and its supplementary materials.
Competing Interest: The authors declare that they have no competing interests.
Funding: The University of Defense (grant number MFVMA/01/18-20) and the Ministry of Education and Science Republic of Serbia (grant number 41018) supported this study. This research received no external funding.
Authors' Contributions: The individual contributions of authors to the manuscript was as follows: MN made substantial contributions to the conception, protocol design and drafting the manuscript; MDj-corresponding author made significant contributions to the interpretation and discussion of the data, writing and editing the final version of the paper; BM contributed to laboratory work and analysis, TBS protocols, preparing microscopic samples and data acquisition; PM performed the histological examination, microscopy and images interpretations; IS performed the histological examination, microscopy and drafting the manuscript; TI made contributions to the conception and applied TBS protocols; NI, contributed to animals supervising, TBS protocols and data acquisition; IS contributed to the conceptualization and editing the manuscript.
All authors approved the submitted manuscript.
All authors have agreed both to be personally accountable for the author's own contributions and to ensure that questions related to the accuracy or integrity of any part of the work, even ones in which the author was not personally involved, are appropriately investigated, resolved, and the resolution documented in the literature.
Corresponding author: Prof. PhD Pharm Mirjana Djukic, the University of Belgrade, Faculty of Pharmacy, Department of Toxicology, Vojvode Stepe 450, 11221 Belgrade, Serbia; [email protected]; Tel.: +381 65 961 0203
Acknowledgments: The authors acknowledged technical staff from the Center of Veterinary Services of Military Health Department, who provided technical help with handling with animals and applying TBS, and the Institute of Medical Research, Military Medical Academy chair, prof. PhD MD Danilo Vojvodic, who provided only general support.
Authors' information:
Name, surname, superscript (affiliation), title/position, initials, and e-mail addresses:
Milica Ninkovic1,2, Prof. PhD MD, MN, [email protected];
Mirjana Djukic3*, Prof. PhD Pharm, MDj, [email protected];
Bojana Mancic2, PhD student MS MD, malicevic.bojana@gmail.com;
Petar Milosavljevic4, PhD Vet Med, PM, [email protected];
Ivana Stojanovic5, Prof. PhD MD, IS, stojanovicivana38@gmail.com;
Tihomir Ilic2, Prof. PhD MD/Dean of the University of Defense, Medical Faculty of the Military Medical Academy, TI, [email protected];
Nela Ilic6, PhD MD, NI, Assoc. Prof. MD, NI, nelavilic@gmail.com
Ivana Stevanovic1,2, Asoc. Prof. PhD Mol Biol, IS, [email protected].
Affiliations:
1Institute of Medical Research, Military Medical Academy, Crnotravska 17, 11 000, Belgrade, Serbia;
2University of Defense, Medical Faculty of the Military Medical Academy, Crnotravska 17, 11 000, Belgrade, Serbia;
3University of Belgrade, Faculty of Pharmacy, Department of Toxicology, Vojvode Stepe 450, 11 221 Belgrade, Serbia;
4 Center of Veterinary Services, Military Health Department, Ministry of Defence, Crnotravska 17, 11 000, Belgrade, Serbia;
5 University of Nis, Faculty of Medicine, Institute for Biochemistry, Bulevar Dr Zorana Djindjica 81, 18 108, Nis, Serbia;
6 University of Belgrade, Medical Faculty, Clinical Center of Serbia, Clinic of Physical Medicine and Rehabilitation, Pasterova 2, 11 000 Belgrade, Serbia.