Funding: AH Maghzi is supported by a clinician-scientist development fellowship from the National Multiple Sclerosis Society and American Brain Foundation.
Conflicts of interest/Competing interests: MK Houtchens has received consulting fees from Biogen, EMD Serono, Sanofi-Genzyme, Mallinckrodt, Roche and research support from Biogen, EMD Serono, and Sanofi-Genzyme. P Preziosa has received speaking fees from Biogen, ExceMED, Merck Serono, and Novartis. C Ionete has received consulting fees from Sanofi-Genzyme, and research support from Biogen, EMD Serono, and Genentech. JM Stankiewicz has received consulting fees from Biogen, BMS/Celgene, EMD Serono, Genentech, Sanofi-Genzyme, and Novartis. A Cabot has received speaking fees from Alexion, Biogen, EMD/Serono, Genentech, Novartis, and Sanofi-Genzyme. JA Sloane has received consulting fees from Biogen, BMS/Celgene, EMD Serono, Genentech, Alexion, and Sanofi-Genzyme, and research support from National MS Society, Genentech, Biogen, EMD Serono, and Sanofi-Genzyme. MS Freedman has received research or educational grants from EMD Serono, Hoffman-La Roche, and Sanofi-Genzyme, and honoraria, consultation, or speaking fees from Actelion, Alexion, Atara, Bayer, Biogen, BMS/Celgene, Clene Nanomedicine, EMD Serono, GRI Bio, Hoffman La-Roche, Magenta Therapeutics, MedDay, Merck Serono, Novartis, Sanofi-Genzyme, and Teva. M Filippi has received consulting and/or speaking fees from Bayer, Biogen Idec, Merck-Serono, Novartis, Roche, Sanofi Genzyme, Takeda, and Teva, and research support from Biogen, Merck-Serono, Novartis, Roche, and Teva. HL Weiner has received consulting fees from Biodextris, Biogen, CBridge Capital, Everest Medicines, Genentech, Tiziana, Tilos, IM Therapeutics, Magnolia, MedDay, and vTv, and research support from Biogen, EMD Serono, Genentech, Sanofi-Genzyme, Google, Novartis; Teva, Tilos, and Verily. R Bakshi has received consulting fees from Bayer, Biogen, BMS/Celgene, EMD Serono, Genentech, and Novartis, and research support from BMS/Celgene, EMD Serono, and Sanofi-Genzyme. The other authors have nothing to disclose.
Ethics approval/Consent to participate: All patients provided consent to be anonymously included in this report.
Consent for publication: All authors have consented to publication.
Availability of data and material/Code availability: NA
Authors’ contributions: RB, MKH and AHM contributed to the conceptualization, gathering of data, drafting and revising the manuscript. PP, CI, BDB, IB, THWS, AC, and MF contributed to data gathering, drafting and revising the manuscript. JMS, ST, JAS, MSF and HLW contributed to drafting and revising the manuscript.