The northwestern Pacific monsoon trough (NWPMT) deeply impacts socio-economic development and human security over East Asia by supplying moisture to the summer monsoon rainfall and modulating tropical cyclone activities. However, considerable inter-model spreads in the Coupled Model Inter-comparison Project Phase 6 models make the future projection of the NWPMT less reliable. Here, we find that the inter-model spread of the NWPMT change is significantly correlated with the central equatorial Pacific sea surface temperature change, and mainly determined by the equatorial thermocline sharpness in the historical simulations. According to the emergent constraint method, the central equatorial Pacific SST would warm up about 8% slower than the multi-model mean with 56% uncertainty reduced. Correspondingly, the NWPMT would slacken westward with 36% uncertainty reduced. Results here emphasize the importance of examining and reducing systematic model biases in simulating subsurface fields that have been overlooked in past literatures, before achieving more reliable future projections.