This study constructs the enterprise-level multi-regional input-output (EMRIO) table, a framework for analyzing global supply chains. The EMRIO table uniquely disaggregates existing sector-level input-output tables into an enterprise-level structure encompassing 71 countries, 11,158 sectors, 9,225 companies, 20,076 segments, and 78,676 subsegments. This approach allows for a detailed breakdown of global economic interactions, extending from individual companies to their diverse business units. The database is constructed by integrating annual security reports, fundamental financial information, business-to-business transactions, and bills of lading into input-output tables, facilitating a granular view of the global operations of enterprises. EMRIO's detailed structure is particularly adept at enhancing the understanding of global value chains and Scope 3 emissions, offering a new lens for examining the intricacies of international trade and corporate environmental impact.