The construction of molecular carbon frameworks stands as the fundamental objective of organic chemistry. The carbon skeleton of each organic molecule serves as the foundation for its three-dimensional structure, playing a pivotal role in determining its physical and biological properties.1 Within the realm of synthesis, the ability to access complex molecules while prioritizing skeletal diversification serves as a crucial factor in advancing the frontiers of efficient synthetic design.2-4 In line with this pursuit, our team has developed a versatile synthetic strategy based on interconversion of complex molecular frameworks which enabled a generalized access to the taxane diterpene family. A wide range of classical and cyclotaxane frameworks was accessed including,among others, the first total syntheses of taxinine K (2), canataxapropellane (5) and dipropellane C from a single advanced intermediate. The synthetic approach deliberately eschews biomimicry, emphasizing instead potency of stereoelectronic control in orchestrating the interconversion of polycyclic frameworks.