In this study, it was aimed to identify the microorganisms isolated from aflatoxin-containing dried figs, the biodegradation of aflatoxin and the products resulting from biodegradation studies. Within the scope of the study, adapted microorganisms in aflatoxin-containing dried figs were isolated and preliminary screening studies were carried out to determine their morphological/molecular identification and aflatoxin degradation properties. In biodegradation studies of aflatoxin, both microorganism cultures and supernatants were examined separately. Aflatoxin biodegradation occurred with the isolated microorganisms Bacillus cereus HBB532, Bacillus safensis HBB 526, Periesta megaterium HBB 522, Zygosaccharomyces rouxii HBB 542 and Zygosaccharomyces pseudorouxii HBB 545. Biodegradation amounts were determined using high pressure liquid chromatography. QTOF-LC/MS analyzes were performed to determine the degradation products formed after biodegradation in the samples where aflatoxin biodegradation took place. With these microorganisms, the amount of aflatoxin in dried figs was reduced by 50% or more. As a result of biodegradation, 22 degradation products were identified. This study is the first aflatoxin biodegradation study conducted using dried figs. In this study, aflatoxin biodegradation was evaluated with the matrix effect.