The difficulty of accessing a proper quality water supply in some rural zones has been an important concern in this area of research. This paper presents four magnetic materials potentially usable in water treatment as alternatives to the traditional use of flocculants based on iron and aluminum salts. These materials were extracted from Stenocereus griseus and Melocactus sp. mucilage and magnetized through modification with magnetite Fe3O4 via the crosslinking method. The effectiveness of the biofloculants and their optimal dosage were determined by performing a jar test for turbidity removal on natural water samples from selected sources. The physical, chemical, and magnetic properties were characterized by Fourier transform infrared spectroscopy, vibrating sample magnetometry, X-ray diffraction and scanning electron microscopy. The effectiveness of each material was evaluated in terms of decreasing percentage of turbidity and reaching an acceptable value of nephelometric turbidity units, NUT, ≤ 2, according to the normativity of the Colombian population. The results showed that magnetic modification of biopolymers, especially mucilage, is a promising alternative for reducing the turbidity of water samples. The work presented here has profound implications for the future application of magnetic materials for water treatment and may eventually help to solve the problems of some rural zones where access to high-quality water is worrisome. This research contributes to the search for solutions to the great social, economic, and environmental problems that the country faces and that are contemplated in the Sustainable Development Goals (SDGs) of the 2030 Agenda of the United Nations.