The cement industry is responsible for approximately 7% of anthropogenic CO2 emissions with low margins and the highest carbon intensity of any industry per unit of revenue. To encourage complete decarbonisation of the cement industry, strategies must be found in which GHG emission reductions are incentivised. Here we show through integrated techno-economic modelling that CO2 mineralisation using silicate minerals results in emission reductions of 6–31% while generating an additional profit of up to €28 per tonne cement. In order to create positive CO2 mineralisation business cases three conditions are paramount: the resulting products must be used as a supplementary material in cement blends, the storage of CO2 in minerals must be eligible for ETS credits or similar, and the feedstock minerals must be available in close proximity ( < ~ 550km, transported by truck and train).