Recent increase in research on the genus Oxyrhopus, which comprises 15 species distributed throughout the entire Neotropical region. Although presence data is available, the potential distribution and temporal stability of these species remain underexplored areas. Understanding the impacts of climate change and the need to identify effective conservation measures is crucial. In this study, the future scenarios of the IPCC are examined, projecting changes up to 2061-2080, using optimistic (SSP2), intermediate (SSP3), and pessimistic (SSP5) scenarios. The use of maximum entropy models to predict the distribution of these snakes both in the present and in the future is emphasized. Available data records from the internet, scientific articles, and museum data were employed, filtered by species, resulting in 6,413 records for model creation. The potential distribution of 14 out of the 15 species of the genus Oxyrhopus was successfully calculated, using specific bioclimatic parameters for each one. Our findings represent the first potential distribution models for Oxyrhopus species. Most species exhibit wide distributions that could be maintained over time according to future scenarios. However, some populations are not represented in the models, suggesting a risk due to suboptimal conditions in the future.