Costs related to the number of hospital admissions due to respiratory diseases (total value and average value)
34,749,023 hospitalizations resulting from RD were recorded in the Brazilian population, during the period from 1998 to 2021, representing a total of R$23,653,000,000.00 reais and an average of R$760.62 reais per hospitalization. For the age group aged less than 1 year to 19 years, designated in the analysis as the young group, the number of hospitalizations corresponded to 16,757,489.00 representing a total value of R$9,053,000,000.00 in the period studied, being an average of R$ 612.48 reais per hospitalization. And for the age group between 20 and over 80 years old, designated in the analysis as the adult group, 17,991,534 hospitalizations were observed, equivalent to R$14,610,000,000.00 reais, and an average of R$871.14 reais per hospitalization (p < 0.0001).
It was observed in the general population that 49.8% of hospital admissions n = 17,299,941 were due to pneumonia, followed by asthma, n = 5,161,825 − 14.9% and bronchitis/emphysema and other chronic obstructive pulmonary diseases n = 3,874 .542 − 11.2%. As for the total amount, expenses equivalent to R$11,415,000,000.00 were spent − 48.3% on hospitalizations for pneumonia; R$6,139,647,955.00–26% due to other diseases of the respiratory system; and R$ 2,303,278,197.00–9.7% for bronchitis, emphysema and other chronic obstructive pulmonary diseases, as shown in Table 1.
The total value data referring to hospital admissions according to the young group, were allocated to pneumonia R$5,056,659,617.00–55.9%; other diseases of the respiratory system R$1,470,595,724.00–16.2% and asthma R$1,238,601,886.00–13.7%. Regarding the adult group, data for pneumonia were R$6,358,136,064.00–43.5%; other diseases of the respiratory system R$4,667,200,207.00–31.9% and bronchitis/emphysema and other chronic obstructive pulmonary diseases R$2,158,036,529.00–14.8%, respectively.
The professional value analyzed, accordindifueg to Brazilian regions, presented costs equivalent to R$2,293,203,559.00 reais. Regarding the list of morbidities, in the general population, pneumonia R$1,077,220,216.00–47%, other diseases of the respiratory system, R$736,478,427.80–32.1%, and chronic diseases of the tonsils and adenoids, R$139,050,136.90–6.1%, obtained higher financial indexes, respectively, represented in Table 1.
When comparing total costs, the group known as adults, over 20 years of age to 80 years or more, is responsible for the highest expenditure on respiratory diseases (p < 0.005) when compared to the group aged up to 19 years. For this age group, defined as the young group, we can highlight higher numbers of hospitalizations for acute pharyngitis and tonsillitis, laryngitis and tracheitis, acute bronchitis and bronchiolitis, chronic diseases of the tonsils and adenoids, asthma (p < 0.001) and other acute infections of upper airways (p < 0.005). The costs, with total, average and professional value when compared to the groups, are shown in Table 1.
Table 1
Distribution of hospital admissions according to the list of morbidity, total value, average value and professional value of the ICD-10 for diseases of the respiratory system, Brazil, 1998–2021. Data from the general population (less than 1 to 80 years or more), the young group (less than 1 year to 19 years) and the adult group (20 and > 80 years).
Distribution of hospital admissions |
Respiratory diseases Young Group vs. Adult Group | No. of hospitalizations (%) | Amount | Average value | Professional Value |
Acute pharyngitis and acute tonsillitis < 1–80 < 1–19 20->80 | 152167 (0.4) 104111 (0, 6)* 48056 (0.3) | R$ 43,334,215.30 R$ 29,633,958.60* R$ 13,700,259.55 | BRL 251.67 BRL 251.31 BRL 252.18 | BRL 5,267,770.91 R$ 3,574,921.82 R$ 1,692,849.09 |
Acute laryngitis and tracheitis < 1–80 < 1–19 20->80 | 706645 (2.0) 468765 (2, 8)* 237880 (1.3) | R$ 126,929,656.00 R$ 85,122,702.00* R$ 41,806,953.10 | R$ 214.25 R$ 216.02 BRL 209.79 | BRL 7,350,305.96 R$ 5,090,084.97* BRL 2,260,220.99 |
Other acute upper respiratory infections < 1–80 < 1–19 20->80 | 360915 (1.0) 228575 (1, 4)# 132340 (0.7) | R$ 109,409,623.00 R$ 54,216,409.10 R$ 55,193,213.20 | R$ 316.33 R$ 226.87 BRL 435.11 | R$ 11,465,160.23 R$ 6,119,252.12 R$ 5,345,908.11 |
Influenza [flu] < 1–80 < 1–19 20->80 | 692751 (2.0) 362318 (2.2) 330433 (1.8) | R$ 424,220,403.00 R$ 199,828,338.40 R$ 224,392,064.60 | BRL 613.27 BRL 570.78 BRL 621.91 | R$ 36,619,195.90 R$ 13,217,424.59 R$ 23,401,771.31* |
Pneumonia < 1–80 < 1–19 20->80 | 17299941 (49.8) 9008490 (53.8) 8291451 (46.1) | R$ 11,415,000,000.00 BRL 5,056,659,617.00 R$ 6,358,136,064.00 | BRL 723.93 BRL 652.13 BRL 762.02 | R$ 1,077,220,216.00 R$ 411,469,010.80 R$ 665,751,205.00# |
Acute bronchitis and acute bronchiolitis < 1–80 < 1–19 20->80 | 1090529 (3.1) 971,947.00 (5, 8)* 118582 (0.7) | R$ 340,576,880.00 R$ 303,259,275.00* R$ 37,317,603.80 | R$ 298.44 R$ 296.18 R$ 291.83 | R$ 35,816,105.72 R$ 31,952,574.91* R$ 3,863,530.81 |
Chronic sinusitis < 1–80 < 1–19 20->80 | 48366 (0.1) 9541 (0.1) 38825 (0, 2)* | R$ 25,098,419.30 R$ 4,669,805.19 R$ 20,428,613.10* | R$ 480.40 BRL 499.13 BRL 476.93 | R$ 8,058,088.58 R$ 1,391,533.54 R$ 6,666,555.04* |
Other diseases of the nose and paranasal sinuses < 1–80 < 1–19 20->80 | 354721 (1.0) 100709 (0.6) 254012 (1.4) | R$ 149,249,858.00 R$ 44,549,744.30 R$ 104,700,115.00 | BRL 389.17 BRL 413.37 R$ 379.30 | R$ 46,649,520.78 R$ 13,871,563.10 R$ 32,777,957.68# |
Chronic diseases of the tonsils and adenoids < 1–80 < 1–19 20->80 | 1035411 (3.0) 939248 (5, 6)* 96163 (0.5) | R$ 380,586,314.00 R$ 345,353,122.00* R$ 35,233,191.80 | BRL 349.35 BRL 350.46 BRL 337.27 | R$ 139,050,136.90 R$ 126,178,727.80* R$ 12,871,409.07 |
Other upper respiratory tract diseases < 1–80 < 1–19 20->80 | 527603 (1.5) 279423 (1.7) 248180 (1.4) | R$ 163,200,934.00 R$ 62,899,110.00 R$ 100,301,827.00* | BRL 384.08 R$ 259.94 BRL 482.53 | R$ 19,730,356.58 R$ 5,826,422.91 R$ 13,903,933.67# |
Bronchitis, emphysema and other chronic obstructive pulmonary diseases < 1–80 < 1–19 20->80 | 3874542 ((11.2) 219978 (1.3) 3654564 (20, 3)* | R$ 2,303,278,197.00 R$ 146,376,727.40 R$ 2,158,036,529.00* | BRL 672.97 BRL 618.97 BRL 683.26 | R$ 109,554,371.30 R$ 11,524,462.17 R$ 98,029,909.17* |
Asthma < 1–80 < 1–19 20->80 | 5161825 (14.9) 320808500 (19, 1)* 1953740 (10.9) | R$ 1,984,801,084.00 R$ 1,238,601,886.00* R$ 745,660,810.00 | BRL 451.25 BRL 448.65 BRL 456.78 | R$ 55,302,806.33 R$ 34,031,225.51* R$ 21,271,580.82 |
Bronchiectasis < 1–80 < 1–19 20->80 | 64021 (0.2) 14287 (0.1) 49734 (0.3) | R$ 48,332,851.00 R$ 10,575,210.30 R$ 37,757,639.40# | BRL 985.34 BRL 942.58 R$ 1,003.76 | R$ 3,800,380.24 R$ 902,440.26 R$ 2,897,939.98# |
Pneumoconiosis < 1–80 < 1–19 20->80 | 13251 (0.0) 1312 (0.0) 11939 (0.1) | R$ 10,625,944.90 R$ 910,137.83 R$ 9,715,807.00* | BRL 806.4 BRL 818.07 BRL 814.63 | R$ 840,715.90 R$ 80,023.91 R$ 760,691.99* |
Other diseases of the respiratory system < 1–80 < 1–19 20->80 | 3366335 (9.7) 840700 (5.0) 2525635 (14, 0)* | R$ 6,139,647,955.00 R$ 1,470,595,724.00 R$ 4,667,200,207.00* | R$ 1,895.70 R$ 2,111.87 R$ 1,846.24 | R$ 736,478,427.80 R$ 164,175,325.70 R$ 572,303,102.10# |
Total < 1–80 < 1–19 20->80 | 34749023 16757489 17991534 | R$ 23,653,000,000.00 R$ 9,053,000,000.00 R$ 14,610,000,000.00 | BRL 760.62 BRL 612.48 BRL 871.14 | R$ 2,293,203,559.00 R$ 829,404,994.10 R$ 1,463,798,565.00# |
Source: Ministry of Health - SUS Hospital Information System (SIH/SUS).
* p < 0.0001, #p < 0.005, Unpaired Student t Test (Young Group vs. Adult Group).
Costs related to the number of hospital admissions for respiratory diseases by region of Brazil (total and average values)
Regarding the longitudinal variation between 1998 and 2021 in hospital costs according to the regions of the country, in the general population there was a significant statistical difference between them, p < 0.0001, showing an increase over the years, demonstrating greater financial support for the Southeast region. It was observed that, from 2008 onwards, there was an increase in this financial contribution to the regions, so that the Southeast region R$9,192,000,000.00–38.9%, the Northeast R$5,782,000,000.00–24.4% and South R$ 5,156,000,000.00–21.8% had higher costs in relation to the total value (Fig. 1 - a), respectively, allocated to respiratory diseases in Brazil during the period analyzed.
When we analyze the total value of costs in the young group, we observe that the Southeast regions R$3,161,293,509.00–36.2%, Northeast R$ 2,623,516,084.00–29% and South R$ 1,541,554,378.00–17%, presented the highest costs, respectively, p < 0.0001 (Fig. 1 - b). For the adult group, costs behaved differently, with the Southeast R$ 5,794,560,808.00–3.7%, the South R$ 3,613,504,931.00–24.7% and the Northeast R$ 3,161,293,509. 00–21.6%, the highest values, respectively, p < 0.0001 (Fig. 1- c).
Figure 1. Temporal analysis of hospital costs according to Brazilian regions due to respiratory diseases between 1998 and 2021. a) general population (p < 0.0001); b) young group (p < 0.0001) and c) adult group (p < 0.0001). Source: Ministry of Health - SUS Hospital Information System (SIH/SUS).
These numbers seem encouraging, however, when we correct the values using the Broad National Consumer Price Index (NCPI), made available by the Brazilian Institute of Geography and Statistics, (IBGE – Brazil), for the respective years of 1998 and 2021, we see a growing discrepancy between what should have been spent and what actually was. Table 2 shows the values corrected for inflation in the years compared.
Table 2
Comparative analysis of hospital costs according to Brazilian regions due to respiratory diseases between 1998 and 2021.
Source: Ministry of Health - SUS Hospital Information System (SIH/SUS).
Region | 1998 Amounts spent | 2021 Amounts spent | Amounts corrected by inflation |
< 1–80 years |
North | R$ 27.699.737,00 | R$ 73.220.785,00 | R$ 231.924.580,99 |
Northeast | R$ 136.000.000,00 | R$ 256.000.000,00 | R$ 1.138.701.895,06 |
Southeast | R$ 181.000.000,00 | R$ 508.00.000,00 | R$ 1.515.478.257,40 |
South | R$ 130.000.000,00 | R$ 273.000.000,00 | R$ 1.088.465.046,75 |
Midwest | R$ 41.892.896,00 | R$ 85.069.287,00 | R$ 350.761.176,95 |
< 1–19 years |
North | R$ 15.916.358,00 | R$ 28.538.041,00 | R$ 133.264.610,42 |
Northeast | R$ 77.119.382,00 | R$ 68.147.689,00 | R$ 645.705.782,57 |
Southeast | R$ 83.961.256,00 | R$ 113.000.000,00 | R$ 702.991.480,29 |
South | R$ 52.004.416,00 | R$ 42.462.503,00 | R$ 435.422.993,02 |
Midwest | R$ 20.390.862,00 | R$ 17.500.350,00 | R$ 170.728.773,54 |
20->80 years |
North | R$ 11.783.379,00 | R$ 44.682.744,00 | R$ 98.659.970,57 |
Northeast | R$ 58.619.108,00 | R$ 188.000.000,00 | R$ 490.806.539,46 |
Southeast | R$ 96.560.808,00 | R$ 395.000.000,00 | R$ 808.485.110,72 |
South | R$ 78.014.580,00 | R$ 230.000.000,00 | R$ 653.201.103,59 |
Midwest | R$ 21.502.034,00 | R$ 67.568.937,00 | R$ 180.032.403,41 |
Regarding the average value of hospital admissions due to RD, during the period evaluated, an average of R$760.00 per admission was observed, and there was no statistically significant difference between the regions (p = 0.1416). An increase of 82.74% was observed, R$1,277.71 reais, when comparing the average hospitalization between 1998 R$266.64 reais and 2021, R$1,544.35 reais, p < 0.0001. However, when corrected for the country's inflation, the value should be R$ 2,232.53 reais.
When comparing the regions, a significant increase was observed in the average value of hospital admission in all regions, with the greatest increase in the South region of 566% (1998 - R$ 295.6 and 2021 - R$ 1970.47), Southeast 461% (1998 - R$ 288.13 and in 2021 R$ 1617.56), and Central-West 602% (1998 - R$ 256.93 and in 2021 R$ 1548.71) when compared between 1998 and 2021.
Evaluating the young group, the average cost of hospitalization was R$612.48 per hospitalization and there was no statistically significant difference between the regions (p = 0.2960). However, behavior over the years showed that the regions that suffered the greatest average increases were: Southeast 408% (1998 - R$ 264.97 and in 2021 R$ 1082.18), South 401% (1998 - R$ 276.06 and R$1107.87), and Central-West 248% (1998 - R$250.76 and in 2021 R$873.23).
In the adult group, the average value is R$871.14, higher than the average value for the general population, but there was no statistically significant difference between the regions (p = 0.2277). However, regions observed with the greatest increases were: Southeast 504% (1998 - R$311.84 and in 2021 R$1,885.04), South 641% (1998 - R$310.23 and in 2021 R$2,301.03) and Midwest 636% (1998 - R$263.07 and in 2021 R$1,936.74).
Although some values have increased significantly, these do not follow the values corrected for inflation in the country, as shown in Fig. 2.
Figure 2. Temporal analysis of the average values and corrected values (by inflation) of hospitalizations according to Brazilian regions for respiratory diseases between 1998 and 2021. a) general population; b) youth group and c) adult group. Source: Ministry of Health - SUS Hospital Information System (SIH/SUS).
Costs related to the number of hospital admissions for respiratory diseases by sex (total value, average value and professional value)
In the general population, a total amount of R$23,653,000,000.00 was allocated to the sexes, so that males spent the most, R$12,822,000,000.00; 54.2%, compared to females, R$ 10,841,000,000.00; 45.8%. However, there was no statistically significant difference between them, p = 0.0508.
When analyzing the age groups, it was observed that in the male, young and adult groups the total amount allocated was distributed as follows: R$5,021,000,000.00 and R$7,800,000,000.00, respectively, while in the female sex, in the youth group the amount of R$4,032,000,000.00 was spent, while for the adult group it was R$6,810,000,000.00.
Regarding the average value of hospital admissions for RD considering the sexes, during the period evaluated, these presented costs of R$735.32 for females and R$783.29 for males, however there was no statistically significant difference, p = 0. 5028 when compared. When adjusted for inflation, the values for the year 2021 should be R$ 2,293.53 for males and R$ 2,167.39 for females. For the young group, males presented an average value of R$ 616.62, and for females R$ 607.38 reais. When adjusted for inflation, the values for the year 2021 should be R$ 2,126.86 for males and R$2,069.17 for male. For the adult group, for males R$ 919.41 and for females R$ 821.51 reais. When adjusted for inflation, the values for the year 2021 should be R$ 2,491.25 for male and R$ 2,259.57 for females. Males had a higher average value spent when compared to females, but there was no statistically significant difference between them (p = 0.7337, p = 0.3809, respectively).
Analysis of deaths from respiratory diseases related to region, age group, sex and morbidity list
1,852,271 deaths due to hospitalizations for respiratory diseases were observed in the general population between 1998 and 2021, with a significant difference being recorded between regions p < 0.0001. The Southeast region had the highest incidence of deaths 49% (n = 907434), followed by the South region 20.9% (n = 386941) and the Northeast region 19.5% (n = 361057), respectively. The age groups with the highest mortality rates in the general population are over 80 years old (31%); 70–79 years old (24%); 60–69 years (17.1%), respectively.
Of the deaths observed in the general population, 54.3%, n = 1006441 were male and 45.7%, n = 845830 were female (p = 0.0049). At the young age group, for males, 54.6%, n = 56167 deaths were recorded and for females 45.4%, n = 46610, showing no statistically significant difference between the sexes, p = 0.0526. For the adult age group, males had more deaths, 54.3%, n = 950274 than females 45.7%, n = 799220, with a statistically significant difference p = 0.0091. Both age groups follow the trend of the population in general.
Regarding the list of morbidities, 49.5%, n = 917338 deaths resulting from pneumonia were observed in the general population, followed by other diseases of the respiratory system 35.6%, n = 659327, and bronchitis/emphysema and other chronic obstructive pulmonary diseases 11.5%, n = 213450, respectively. At the young age group, two ICDs together account for approximately 100% of deaths, they are: pneumonia 48%, n = 4301 and other diseases of the respiratory system 45.1%, n = 46356. For the adult age group, we observed the following behavior: most deaths are caused by pneumonia 49.6%, n = 868037, followed by other diseases of the respiratory system 35%, n = 612971 and bronchitis/emphysema and other lung diseases chronic obstructive 12.2%, n = 212814.
Analysis of the average hospital stay for respiratory diseases related to region, age group, sex and morbidity list
The inferential analysis regarding the average length of hospital stay by region shows a statistically significant difference between regions, p < 0.0001. When looking at the average hospital stay of the general population during the period evaluated, the Southeast and South regions presented 5.9 and 5.2 days, respectively. While the Northeast and Central-West regions were equivalent with 4.8 days and, finally, the North region had an average length of stay of 4.6 days. This pattern was identified for the other young and adult age groups (Fig. 3).
Figure 3. Temporal analysis of the average hospital stay according to Brazilian regions due to respiratory diseases between 1998 and 2021. a) general population (p < 0.0001); b) young group (p < 0.0001) and c) adult group (p < 0.0001). Source: Ministry of Health - SUS Hospital Information System (SIH/SUS).
The highest rates of average days of stay evaluating the days of hospital stay were found in the age groups 60 to 69 years − 6.4; 70 to 79 years old − 6.4; 80 years and over − 6.4 demonstrating higher averages p < 0.0001.
According to ICD-10, the three main diseases for which patients remain hospitalized for the most days were: pneumoconiosis with an average of 8.9; other diseases of the respiratory system 8.6 and bronchiectasis 8.4, respectively, shown in Table 3.
Table 3
Distribution of average and days of hospital stay according to the ICD-10 morbidity list for respiratory system diseases, Brazil, 1998–2021. Including data from the general population (less than 1 to 80 years or more), the young group (less than 1 year to 19 years) and the adult group (20 and > 80 years).
Respiratory diseases Young Group vs. Adult Group | Average permanence hospital | Days of stay hospital |
Acute pharyngitis and acute tonsillitis < 1–80 < 1–19 20->80 | 54.2 67.0 73.5 | 2.9 2.8 3.0 |
Laryngitis and tracheitis high-pitched < 1–80 < 1–19 20->80 | 58.2 72.2 78.7 | 3.2 3.1 3.4 |
Other acute upper airway infections < 1–80 < 1–19 20->80 | 67.4 73.9 101.5 | 3.3 2.9 4.0 |
Influenza [flu] < 1–80 < 1–19 20->80 | 87.1 103.1 115.9 | 4.8 4.7 5.0 |
Pneumonia < 1–80 < 1–19 20->80 | 108.6 123.0 151.1 | 5.7 5.1 6.3 |
Acute bronchitis and acute bronchiolitis < 1–80 < 1–19 20->80 | 78.0 98.9 90.7 | 4.1 4.1 4.1 |
Sinusitis chronicle < 1–80 < 1–19 20->80 | 44.5 61.5 55.4 | 2.3 2.6 2.2 |
Other diseases of the nose and paranasal sinuses < 1–80 < 1–19 20->80 | 24.9 29.0 32.5 | 1.2 1.2 1.3 |
Chronic diseases of the tonsils and adenoids < 1–80 < 1–19 20->80 | 17.3 21.6 27.5 | 0.9 0.9 1.1 |
Other upper respiratory tract diseases < 1–80 < 1–19 20->80 | 61.8 74.3 83.2 | 3.2 3.1 3.4 |
Bronchitis, emphysema and other chronic obstructive pulmonary diseases < 1–80 < 1–19 20->80 | 112.7 179.0 147.5 | 5.9 4.3 6.0 |
Asthma < 1–80 < 1–19 20->80 | 58.5 71.1 80.2 | 3.1 3.0 3.4 |
Bronchiectasis < 1–80 < 1–19 20->80 | 159.9 149.7 221.5 | 8.4 5.9 9.1 |
Pneumoconiosis < 1–80 < 1–19 20->80 | 169.2 155.4 221.9 | 8.9 6.5 9.1 |
Other diseases of the respiratory system < 1–80 < 1–19 20->80 | 163.8 218.7 206.3 | 8.6 8.7 8.6 |
Source: Ministry of Health - SUS Hospital Information System (SIH/SUS).
p > 0.05, Unpaired Student t Test (Young Group vs. Adult Group).
In the analysis by sex in relation to the average hospital stay, in the general population, males had an average of 5.4 days of stay, and females had an average of 5.1 days, with a statistically significant difference, p = 0. 0085. In both groups, the average length of stay behaves similarly; in the young group, males had 4.4 and females had 4.4. In the adult group, for males 6.4 and for females 5.7 days.
Thus, the behavior is the same as the overall age group, so that males have a higher average hospital stay when compared to females, but only the adult group presents statistical differences with p = 0.0001, while for the young group, p = 0.2113, there was no statistical difference.