Study design
The researchers followed a quasi-experimental research design (one group pre and posttest) to conduct the current study. In this design a single group of research participants is pretested, independent variable manipulated, and then post-tested without random assignment [21]. The Trend Checklist for non-randomized trials was followed in this research.
Setting:
The current study was carried out at Mansoura University's Faculty of Nursing, located in Mansoura city, Egypt. The faculty comprises four floors, each serving a different purpose. There appear to be two amphitheaters on the bottom floor, along with offices for student affairs, an activities area for student welfare, and other administrative spaces. There is an amphitheater, two computer labs, and a meeting room on the first floor. The faculty dean's and vice dean's offices, two exam control rooms, a digital library, a book library, a quality and accreditation unit, and a public health unit are all located on the second level. It appears that the vice dean for student affairs' office, the postgraduate affairs office, and nursing skill labs are located on the third level. Lastly, the vice dean of postgraduate studies' office, academic staff offices, and two language laboratories make up the fourth level.
Participants:
Three hundred and fifty undergraduate nursing students who were currently registered in 4 academic levels at the Faculty of Nursing - Mansoura University were enrolled in the current study.
Sampling size and Sampling technique:
The undergraduate nursing students from every academic level were selected by the researchers using a convenience sample technique. First and second-academic-level students were recruited from the Medical/ Surgical Nursing Department, third-academic-level students were recruited from Woman’s Health and Midwifery Department while fourth-academic level students were recruited from Community Health Nursing Department.
The sample size was determined using the Steve Thompson formula, with a 5% ∞ error (95.0% significance) and a 20.0 β error (80.0% research power).
Z is the matching standard class of significance, where n is the sample size, N is the total society size (3970 students), P = percentage of character and objectivity availability = (0.5), d = error percentage = 0.d d = error percentage = 1.96. 350 students were determined to be the sample size.
Table (I): Distribution of the selected undergraduate nursing students from each academic level
Study tool: A self-administrative structured questionnaire. The researchers distributed this tool virtually in a Google form; It was divided into the following four parts:
Part 1: Demographic characteristics. It was produced by the researchers and included six items; age, sex, residence, cellphone number, and academic email and level [23].
Part 2: Knowledge regarding COVID-19 vaccination. It was developed by the researchers. Knowledge questions classified into 9 categories with total number of 42 items; mechanism of action (n=4), importance (n=2), main types (n=3), eligible population (n=9), common side effects (n=9), helpful tips to relieve common side effects (n=4) and serious adverse events (n=5) of COVID-19 vaccination, required measure before getting COVID-19 vaccination (n=4) and time to call the doctor after COVID-19 vaccination (n=2).
Scoring system: Every right response received a score of one, while incorrect and unclear responses received a score of zero. The total scores for the students’ knowledge were calculated by summing all knowledge items scores which ranged from 0 to 42 marks. Overall greater scores indicated a better knowledge about COVID-19 vaccination [24, 25, 26].
Part 3: Vaccination Attitudes Examination (VAX) Scale. This scale was adapted from Martin [27]. to assess nursing students’ negative attitudes regarding COVID-19 vaccination. It consisted of 12 statements covering four subscales (1, 2, 3 = mistrust of vaccine benefit; 4, 5, 6 = worries over unforeseen future effects; 7, 8, 9 = concerns about commercial profiteering; 10, 11, 12 = preference for natural immunity).
Scoring system; each statement is scored on a five-point Likert rating scale coded from 1 to 5. Each of the four subscales was grouped into three levels; low (answer 1, 2; scores from 3-6), intermediate (answer 3 or 4; scores from 7-12), or very/ high (answer 5; scores from 13-15) levels of negative attitudes towards COVID-19 vaccination.
Part 4: COVID-19 Vaccine Hesitancy Scale. It’s a seven-item scale adapted from Freeman [28] to evaluate undergraduate nursing students' hesitation to get the COVID-19 vaccine. Scoring system: Response options specific to each issue, coded from 1 to 5, were employed. Additionally, there is a "Don't know" choice that is not counted toward scoring. The total scores for hesitation varied from 7 to 35, with higher scores corresponding to greater hesitancy to the COVID-19 vaccine. The total hesitancy scores were categorized into three levels; willing (answer 1 or 2; scores from 7-14), doubtful (answer 3; scores from 15-21), or strongly hesitant (answer 4 or 5; scores from 22-35) to have the COVID-19 vaccine.
Validity:
A panel of five experts from the Mansoura University Faculty of Nursing, with backgrounds in Medical-Surgical Nursing, Women's Health and Midwifery, and Community Health Nursing, evaluated the content validity of the developed and modified sections of the study tool based on factors such as length, overall appearance, format, wording, content, item sequence, clarity, and coverage. The third component of the study tool, the statements of mistrust on the vaccine benefit subscale of the VAX Scale, were changed from positive to negative by the researchers. In the COVID-19 Vaccine Hesitancy Scale declarations, the researchers changed a few things. The researchers made the necessary adjustments after the experts evaluated the study tool.
Content reliability:
The internal consistency of the study instrument was evaluated using the Cronbach's alpha coefficient test (r = 0.84, 0.99, and 0.76 for sections 2, 3, and 4, respectively).
Pilot study:
The researchers conducted a pilot study on 10% of the studied undergraduate students (N=35) who were excluded from the study to evaluate the study tools' clarity, feasibility and applicability, to recognize the expected obstacles which may hinder data collection. The researchers conducted a pilot study on 10% of the studied undergraduate students (N=35) who were excluded from the study to evaluate the study tools' clarity, feasibility and applicability, to recognize the expected obstacles which may hinder data collection.
Procedure:
Preparation of the work through:
1. Administrative approval. An approval was received to carry out the research by the researchers through the submission of an official letter from the Faculty dean to the vice dean of education and studies affairs at the Faculty of Nursing, Mansoura University.
2. Ethical considerations. The researchers obtained ethical approval from the Research Ethics Committee of the Faculty of Nursing, Mansoura University (IRP: Ref. no. P.0518) and written informed consent from the participants. The researchers introduced themselves and explained the study’s objectives simply to the studied undergraduate nursing students. They affirmed that it was entirely optional for them to take part in the study. Confidentiality was guaranteed, and the data and answers from the students were handled anonymously and used exclusively for the study. The findings were incorporated into the essential research and used in subsequent publications. Individuals were advised that their accomplishment scores would not be impacted by their decision to quit the study whenever they want and without explanation.
Study framework:
The researchers collected data throughout 2 months (August and September 2021). The framework of this study was carried out throughout four phases as the following:
Phase (1): Preliminary assessment phase: During the study vocation, the students attended the faculty of nursing for vaccination registration (either to confirm the vaccination appointment or to postpone for a specific reason, such as pregnancy or lactation). During registration day, the researchers had face-to-face meetings with the undergraduate nursing students. As they waited to register in the study hall, the researchers gave an overview of the goals and parameters of the ongoing investigation. Informed consent in writing, academic correspondence, phone numbers, and the consent of the participating students were obtained. The researchers created a group on What's App. A Google form included preliminary assessment data regarding students’ demographic characteristics, knowledge, attitude, and hesitancy regarding COVID-19 vaccination was sent to the group.
Phase (2): Designing of the educational sessions: The researchers designed the educational sessions in the form of a printed English booklet as a simplified handout considering the preliminary assessment data and recent literature. Booklet outlines were foreground, objectives, content, and references. The booklet content was arranged in four parts; definition and types, importance and mechanism of action, eligible population, and what to expect after getting COVID-19 vaccination. The booklet content included 17 messages which supported with pictures with sharp resolution, true color, and contrast and focused on what the undergraduate nursing students need to know and do.
Booklet messages were the definition and types of COVID-19 vaccination, the importance, and mechanism of action and benefits of COVID-19 vaccine, the difference between the immunity developed from getting COVID-19 infection and immunity from getting a COVID-19 vaccine, safety and effectiveness of COVID -19 vaccination, how long does protection from vaccination last? Myths and facts of vaccination, the eligible population of vaccination, what to expect when getting vaccination? Common side effects of vaccination, helpful tips to relieve common side effects of vaccination, serious and rare adverse events following vaccination, and time to call the doctor after vaccination were also included in the booklet messages.
Phase (3): Implementation of the virtual educational sessions
The researchers conducted two virtual educational sessions via online Microsoft Teams after a previously scheduled time suitable for undergraduate nursing students. The links were sent to the WhatsApp group. Each session included specific objectives, estimated time, and educational materials and methods. The researchers presented two parts of the study content for 2 hours meeting each session.
Regarding sessions delivery, the researchers presented the content using multimodal educational methods and materials; interactive presentation, discussion, brainstorming, and booklet about COVID-19 vaccination. The researchers distributed the booklet virtually to the undergraduate nursing students, explained each point regarding COVID-19 vaccination throughout the sessions. Additionally, the booklet was sent on the WhatsApp group to be available for the students to review.
Phase (4): Evaluation of the effectiveness of the virtual educational sessions: At the end of the last session and before the students attended their second appointment for vaccination, the researchers carried out the post-test as the link was sent on the WhatsApp group included the same tool used for the pre-test.
Statistical analysis:
Following collection, data were coded, categorized, sorted, and then moved into formats specifically created for computer feeding. The statistical program SPSS v23, which stands for Statistical Package for the Sconces, was used to conduct the statistical analysis.
Descriptive statistics were used to show the data as percentages and frequencies. For continuous variables, the arithmetic mean ± standard deviation and median were employed, whereas percentages were utilized for categorical variables. To compute changes over time for qualitative variables, Monte Carlo (MC) tests and chi-square (X2) of association were employed. For quantitative variables, the Wilcoxon Sign Ranked Test and the Paired T-test were utilized to compare two paired individuals within a single group. T-test in pairs for variables with normally distributed data. For variables whose data deviated from a normal distribution, the Wilcoxon-Signed Ranks test was employed. To determine if there was a positive or negative correlation between two quantitative variables, the Pearson correlation coefficient test was utilized. If P was more than 0.05, the final results were deemed not significant and significant if P< = 0.05.