1. Choo AM, Liu J, Dvorak M, Tetzlaff W, Oxland TR: Secondary pathology following contusion, dislocation, and distraction spinal cord injuries. Exp Neurol 2008;212:490-506.
2. Kwon BK, Tetzlaff W, Grauer JN, Beiner J, Vaccaro AR: Pathophysiology and pharmacologic treatment of acute spinal cord injury. Spine J 2004;4:451-464.
3. Hausmann ON: Post-traumatic inflammation following spinal cord injury. Spinal Cord 2003;41:369-378.
4. Donnelly DJ, Popovich PG: Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury. Exp Neurol 2008;209:378-388.
5. Trivedi A, Olivas AD, Noble-Haeusslein LJ: Inflammation and Spinal Cord Injury: Infiltrating Leukocytes as Determinants of Injury and Repair Processes. Clin Neurosci Res 2006;6:283-292.
6. Chavarria A, Alcocer-Varela J: Is damage in central nervous system due to inflammation? Autoimmun Rev 2004;3:251-260.
7. Adolf A, Rohrbeck A, Munster-Wandowski A, Johansson M, Kuhn HG, Kopp MA, Brommer B, Schwab JM, Just I, Ahnert-Hilger G, Holtje M: Release of astroglial vimentin by extracellular vesicles: Modulation of binding and internalization of C3 transferase in astrocytes and neurons. Glia 2019;67:703-717.
8. Hira K, Ueno Y, Tanaka R, Miyamoto N, Yamashiro K, Inaba T, Urabe T, Okano H, Hattori N: Astrocyte-Derived Exosomes Treated With a Semaphorin 3A Inhibitor Enhance Stroke Recovery via Prostaglandin D2 Synthase. Stroke 2018;49:2483-2494.
9. Huang S, Ge X, Yu J, Han Z, Yin Z, Li Y, Chen F, Wang H, Zhang J, Lei P: Increased miR-124-3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons. FASEB J 2018;32:512-528.
10. Mohr AM, Mott JL: Overview of microRNA biology. Semin Liver Dis 2015;35:3-11.
11. Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004;116:281-297.
12. Fabian MR, Sonenberg N, Filipowicz W: Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem 2010;79:351-379.
13. Ji ZC, Han SH, Xing YF: Overexpression of miR-3196 suppresses cell proliferation and induces cell apoptosis through targeting ERBB3 in breast cancer. Eur Rev Med Pharmacol Sci 2018;22:8383-8390.
14. Hosseinahli N, Aghapour M, Duijf PHG, Baradaran B: Treating cancer with microRNA replacement therapy: A literature review. J Cell Physiol 2018;233:5574-5588.
15. Thery C, Zitvogel L, Amigorena S: Exosomes: composition, biogenesis and function. Nat Rev Immunol 2002;2:569-579.
16. Tkach M, Thery C: Communication by Extracellular Vesicles: Where We Are and Where We Need to Go. Cell 2016;164:1226-1232.
17. Iero M, Valenti R, Huber V, Filipazzi P, Parmiani G, Fais S, Rivoltini L: Tumour-released exosomes and their implications in cancer immunity. Cell Death Differ 2008;15:80-88.
18. King HW, Michael MZ, Gleadle JM: Hypoxic enhancement of exosome release by breast cancer cells. BMC Cancer 2012;12:421.
19. Guo X, Qiu W, Liu Q, Qian M, Wang S, Zhang Z, Gao X, Chen Z, Xue H, Li G: Immunosuppressive effects of hypoxia-induced glioma exosomes through myeloid-derived suppressor cells via the miR-10a/Rora and miR-21/Pten Pathways. Oncogene 2018;37:4239-4259.
20. Giurisato E, Xu Q, Lonardi S, Telfer B, Russo I, Pearson A, Finegan KG, Wang W, Wang J, Gray NS, Vermi W, Xia Z, Tournier C: Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. Proc Natl Acad Sci U S A 2018;115:E2801-E2810.
21. Ding N, Wang Y, Dou C, Liu F, Guan G, Wei K, Yang J, Yang M, Tan J, Zeng W, Zhu C: Physalin D regulates macrophage M1/M2 polarization via the STAT1/6 pathway. J Cell Physiol 2019;234:8788-8796.
22. Mosser DM, Edwards JP: Exploring the full spectrum of macrophage activation. Nat Rev Immunol 2008;8:958-969.
23. Stout RD, Suttles J: Functional plasticity of macrophages: reversible adaptation to changing microenvironments. J Leukoc Biol 2004;76:509-513.
24. Gensel JC, Zhang B: Macrophage activation and its role in repair and pathology after spinal cord injury. Brain Res 2015;1619:1-11.
25. Kong X, Gao J: Macrophage polarization: a key event in the secondary phase of acute spinal cord injury. J Cell Mol Med 2017;21:941-954.
26. Ji XC, Dang YY, Gao HY, Wang ZT, Gao M, Yang Y, Zhang HT, Xu RX: Local Injection of Lenti-BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice. Cell Mol Neurobiol 2015;35:881-890.
27. Ma SF, Chen YJ, Zhang JX, Shen L, Wang R, Zhou JS, Hu JG, Lu HZ: Adoptive transfer of M2 macrophages promotes locomotor recovery in adult rats after spinal cord injury. Brain Behav Immun 2015;45:157-170.
28. Qian M, Wang S, Guo X, Wang J, Zhang Z, Qiu W, Gao X, Chen Z, Xu J, Zhao R, Xue H, Li G: Hypoxic glioma-derived exosomes deliver microRNA-1246 to induce M2 macrophage polarization by targeting TERF2IP via the STAT3 and NF-kappaB pathways. Oncogene 2019;10.1038/s41388-019-0996-y
29. Peng Z, Gao W, Yue B, Jiang J, Gu Y, Dai J, Chen L, Shi Q: Promotion of neurological recovery in rat spinal cord injury by mesenchymal stem cells loaded on nerve-guided collagen scaffold through increasing alternatively activated macrophage polarization. J Tissue Eng Regen Med 2018;12:e1725-e1736.
30. Gosselin RD, Meylan P, Decosterd I: Extracellular microvesicles from astrocytes contain functional glutamate transporters: regulation by protein kinase C and cell activation. Front Cell Neurosci 2013;7:251.
31. Sakha S, Muramatsu T, Ueda K, Inazawa J: Exosomal microRNA miR-1246 induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma. Sci Rep 2016;6:38750.
32. Guo X, Xue H, Shao Q, Wang J, Guo X, Chen X, Zhang J, Xu S, Li T, Zhang P, Gao X, Qiu W, Liu Q, Li G: Hypoxia promotes glioma-associated macrophage infiltration via periostin and subsequent M2 polarization by upregulating TGF-beta and M-CSFR. Oncotarget 2016;7:80521-80542.
33. Tadokoro H, Umezu T, Ohyashiki K, Hirano T, Ohyashiki JH: Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells. J Biol Chem 2013;288:34343-34351.
34. Li L, Li C, Wang S, Wang Z, Jiang J, Wang W, Li X, Chen J, Liu K, Li C, Zhu G: Exosomes Derived from Hypoxic Oral Squamous Cell Carcinoma Cells Deliver miR-21 to Normoxic Cells to Elicit a Prometastatic Phenotype. Cancer Res 2016;76:1770-1780.
35. Guo X, Qiu W, Wang J, Liu Q, Qian M, Wang S, Zhang Z, Gao X, Chen Z, Guo Q, Xu J, Xue H, Li G: Glioma exosomes mediate the expansion and function of myeloid-derived suppressor cells through microRNA-29a/Hbp1 and microRNA-92a/Prkar1a pathways. Int J Cancer 2019;144:3111-3126.
36. Kanichai M, Ferguson D, Prendergast PJ, Campbell VA: Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: a role for AKT and hypoxia-inducible factor (HIF)-1alpha. J Cell Physiol 2008;216:708-715.
37. Li H, Jiang T, Li MQ, Zheng XL, Zhao GJ: Transcriptional Regulation of Macrophages Polarization by MicroRNAs. Front Immunol 2018;9:1175.