1. World Health Organization. Cardiovascular diseases (CVDs). 2017. https://www.who.int/en/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds). Accessed 24 Jul 2020.
2. Ravnskov U, Diamond DM, Hama R, Hamazaki T, Hammarskjold B, Hynes N, et al. Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review. BMJ Open. 2016; 6:e010401.
3. Barter P, Gotto AM, LaRosa JC, Maroni J, Szarek M, Grundy SM, et al. HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events. N Engl J Med. 2007; 357:1301-10.
4. Cholesterol Treatment Trialists' (CTT) Collaborators. The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet. 2012; 380:581-90.
5. World Health Organization. Global health and aging. 2011. https://www.who.int/ageing/publications/global_health.pdf?ua=1. Accessed 24 Jul 2020.
6. Yazdanyar A, Newman AB. The burden of cardiovascular disease in the elderly: morbidity, mortality, and costs. Clin Geriatr Med. 2009; 25:563-77.
7. Lozano JV, Pallares V, Cea-Calvo L, Llisterri JL, Fernandez-Perez C, Marti-Canales JC, et al. Serum lipid profiles and their relationship to cardiovascular disease in the elderly: the PREV-ICTUS study. Curr Med Res Opin. 2008; 24:659-70.
8. Zimetbaum P, Frishman WH, Ooi WL, Derman MP, Aronson M, Gidez LI, et al. Plasma-lipids and lipoproteins and the incidence of cardiovascular-disease in the very elderly - the Bronx Aging Study. Arterioscler Thromb. 1992; 12:416-23.
9. Hayashi T, Kawashima S, Itoh H, Yamada N, Sone H, Watanabe H, et al. Low HDL cholesterol is associated with the risk of stroke in elderly diabetic individuals changes in the risk for atherosclerotic diseases at various ages. Diabetes Care. 2009; 32:1221-3.
10. Weverling-Rijnsburger AWE, Jonkers IJAM, van Exel E, Gussekloo J, Westendorp RGJ. High-density vs low-density lipoprotein cholesterol as the risk factor for coronary artery disease and stroke in old age. Arch Intern Med. 2003; 163:1549-54.
11. Maihofer AX, Shadyab AH, Wild RA, LaCroix AZ. Associations between serum levels of cholesterol and survival to age 90 in postmenopausal women. J Am Geriatr Soc. 2020; 68:288-96.
12. Cheol Seong S, Kim YY, Khang YH, Heon Park J, Kang HJ, Lee H, et al. Data Resource Profile: the National Health Information Database of the National Health Insurance Service in South Korea. Int J Epidemiol. 2017; 46:799-800.
13. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972; 18:499-502.
14. Son KY, Shin DW, Lee JE, Kim SH, Yun JM, Cho B. Association of timed up and go test outcomes with future incidence of cardiovascular disease and mortality in adults aged 66 years: Korean national representative longitudinal study over 5.7 years. BMC Geriatr. 2020; 20:111.
15. World Health Organization, Regional Office for the Western Pacific. The Asia-Pacific perspective: redefining obesity and its treatment. 2000. https://apps.who.int/iris/handle/10665/206936. Accessed 24 Jul 2020.
16. Son KY, Shin DW, Yang HK, Yun JM, Chun SH, Lee JK, et al. Effect of one-time brief additional counseling on periodic health examination for 40- and 66-year-olds: 2-Year follow up of 101 260 participants. Geriatr Gerontol Int. 2018; 18:329-37.
17. Upmeier E, Lavonius S, Lehtonen A, Viitanen M, Isoaho H, Arve S. Serum lipids and their association with mortality in the elderly: a prospective cohort study. Aging Clin Exp Res. 2009; 21:424-30.
18. Takata Y, Ansai T, Soh I, Awano S, Nakamichi I, Akifusa S, et al. Serum total cholesterol concentration and 10-year mortality in an 85-year-old population. Clin Interv Aging. 2014; 9:293-300.
19. Pekkanen J, Linn S, Heiss G, Suchindran CM, Leon A, Rifkind BM, et al. Ten-year mortality from cardiovascular disease in relation to cholesterol level among men with and without preexisting cardiovascular disease. N Engl J Med. 1990; 322:1700-7.
20. Raiha I, Marniemi J, Puukka P, Toikka T, Ehnholm C, Sourander L. Effect of serum lipids, lipoproteins, and apolipoproteins on vascular and nonvascular mortality in the elderly. Arterioscler Thromb Vasc Biol. 1997; 17:1224-32.
21. Abbott RD, Yano K, Hakim AA, Burchfiel CM, Sharp DS, Rodriguez BL, et al. Changes in total and high-density lipoprotein cholesterol over 10- and 20-year periods (the Honolulu Heart Program). Am J Cardiol. 1998; 82:172-8.
22. Krumholz HM, Seeman TE, Merrill SS, Deleon CFM, Vaccarino V, Silverman DI, et al. Lack of association between cholesterol and coronary heart-disease mortality and morbidity and all-cause mortality in persons older than 70 years. JAMA. 1994; 272:1335-40.
23. Sacco RL, Benson RT, Kargman DE, Boden-Albala B, Tuck C, Lin IF, et al. High-density lipoprotein cholesterol and ischemic stroke in the elderly: the Northern Manhattan Stroke Study. JAMA. 2001; 285:2729-35.
24. Fulcher J, Mihaylova B, O'Connell R, Emberson J, Blackwell L, Reith C, et al. Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials. Lancet. 2019; 393:407-15.
25. Zampelas A, Magriplis E. New Insights into Cholesterol Functions: A Friend or an Enemy? Nutrients. 2019; 11:1645.
26. Katsumata Y, Todoriki H, Higashiuesato Y, Yasura S, Ohya Y, Willcox DC, et al. Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project. J Alzheimers Dis. 2013; 34:273-9.
27. Weiss A, Beloosesky Y, Schmilovitz-Weiss H, Grossman E, Boaz M. Serum total cholesterol: a mortality predictor in elderly hospitalized patients. Clin Nutr. 2013; 32:533-7.
28. Mielke MM, Xue QL, Zhou J, Chaves PH, Fried LP, Carlson MC. Baseline serum cholesterol is selectively associated with motor speed and not rates of cognitive decline: the Women's Health and Aging Study II. J Gerontol A Biol Sci Med Sci. 2008; 63:619-24.
29. Okoro CA, Zhong YN, Ford ES, Balluz LS, Strine TW, Mokdad AH. Association between the metabolic syndrome and its components and gait speed among US adults aged 50 years and older: a cross-sectional analysis. BMC Public Health. 2006; 6:282.
30. Ravnskov U. High cholesterol may protect against infections and atherosclerosis. QJM. 2003; 96:927-34.
31. Ravnskov U, McCully KS. Infections may be causal in the pathogenesis of atherosclerosis. Am J Med Sci. 2012; 344:391-4.
32. Werle MH, Moriguchi E, Fuchs SC, Bruscato NM, de Carli W, Fuchs FD. Risk factors for cardiovascular disease in the very elderly: results of a cohort study in a city in southern Brazil. Eur J Cardiovasc Prev Rehabil. 2011; 18:369-77.
33. Corriere M, Rooparinesingh N, Kalyani RR. Epidemiology of diabetes and diabetes complications in the elderly: an emerging public health burden. Curr Diab Rep. 2013; 13:805-13.
34. Verges BL. Dyslipidaemia in diabetes mellitus - Review of the main lipoprotein abnormalities and their consequences on the development of atherogenesis. Diabetes Metab. 1999; 25:32-40.
35. Cannon CP. Mixed dyslipidemia, metabolic syndrome, diabetes mellitus, and cardiovascular disease: clinical implications. Am J Cardiol. 2008; 102:5L-9L.
36. Benfante R, Reed D, Frank J. Does cigarette smoking have an independent effect on coronary heart disease incidence in the elderly? Am J Public Health. 1991; 81:897-9.