2.1 Patient’s clinical data:
We collected the clinical data of 850 patients who underwent both colonoscopy and Helicobacter pylori in endoscopic room of our hospital from January 2018 year to January 2019 year.Among these patients,there were 420 males,430 females.304 patients were helicobacter pylori positive,and 546 patients were helicobacter pylori negative. Among helicobacter pylori positive patients,there were 162 patients have helicobacter pylori eradicated,and 142 patients have not eradicated. In control group,there were 213 patients who’s age over 60 years,and 202 patients who’s age less than 60 years. In polyp group,there were 220 patients who’s age over 60 years,and 215 patients who’s age less than 60 years. In Table 1,there were no significant difference in sex and age aspects of two groups.
Table 1 The comparison of sex and age aspects between two groups
|
Control group
|
Polyp group
|
chisquare
|
P value
|
Sex
male
female
|
205
210
|
215
220
|
0.000
|
0.994
|
Age
>60 years
≤60 years
|
213
202
|
220
215
|
0.048
|
0.827
|
2.2 The colonic polyp and Helicobacter pylori infection
The polyp group have 435 patients,in which there were 192 helicobacter pylori positive patients,and 243 helicobacter pylori negative patients.The percentage of helicobacter pylori positive was 44.1% in polyp group. The control group have 415 patients,in which there were 112 helicobacter pylori positive patients,and 303 helicobacter pylori negative patients.The percentage of helicobacter pylori positive was 36.9% in control group. Through SPSS software analysis,the infection rate of helicobater pylori was higher in polyp group,and there was significant difference. The results shown in Table 2.
Table 2 The helicobacter pylori infection in two groups
|
helicobacter pylori positive
|
helicobacter pylori negative
|
chsiquare
|
P value
|
Control group
|
112
|
303
|
27.191
|
0.000
|
Polyp group
|
192
|
243
|
2.3 The relationship among helicobacter pylori infection,eradication treatment and recurrence of colonic polyp.
Through SPSS software analysis,the recurrence rate of helicobacter pylori positive patients were more higher than helicobacter pylori negative patients. The recurrence rate of helicobacter pylori eradication group was lower than helicobacter pylori no eradication group,and there was significant difference.The results shown in Table 3.
Table 3 The relationship among helicobacter pylori infection,eradication treatment and recurrence of colonic polyp.
|
recurrence
|
chsiquare
|
P value
|
HP infection
positive
negative
|
158
185
|
26.552
|
0.000
|
HP positive
eradication
No eradication
|
75
95
|
13.034
|
0.000
|
2.4 The impact factor of the recurrence of colonic polyp.
Through SPSS software analysis,the impact factor of the recurrence of colonic polyp include helicobacter pylori infection,pathological type of polyp and the number of polyps.There was significant difference.The recurrence rate of helicobacter pylori positive,adenomatous polyps and multiple polyps were more higher.
The results were shown in Table 4.
Table 4 The impact factor of the recurrence of colonic polyp.
|
recurrence
|
No recurrence
|
chsiquare
|
P value
|
Sex male
female
|
205
202
|
215
228
|
0.286
|
0.593
|
Age ≤60 years
>60years
|
125
118
|
282
325
|
1.726
|
0.189
|
Polyp size
diameter<1cm
diameter≥1cm
|
210
185
|
250
205
|
0.270
|
0.603
|
Helicobacter pilori
positive
negative
|
202
185
|
102
361
|
83.500
|
0.000
|
Polyp site
Ileocecus
Colon ascendens
Colon transversum
Colon descendens
Colon sigmoideum
Rectum
|
62
53
75
65
78
60
|
77
68
86
72
85
69
|
0.701
|
0.983
|
pathological type
Inflammation polyp
Hyperplasia polyp
Adenomatous polyp
|
92
120
152
|
150
176
162
|
6.913
|
0.032
|
Number of polyps
Single
Multiple
|
182
235
|
268
165
|
28.394
|
0.000
|