Acknowledgments: The authors thank Drs. Ayumi Goda, Mike Saji, Munenori Ikegami, Munehisa Sakamoto, Makoto Takei, Shintaro Nakano, and all the investigators, clinical research coordinators, and institutions involved in the administration of the WET-HF registry.
Author Contributions: Yusuke Yamazaki, Yasuyuki Shiraishi, Yuji Nagatomo, Takashi Kohno, Tsutomu Yoshikawa collected data and check the manuscript. Yusuke Yamazaki, Yasuyuki Shiraishi and Shun Kohsaka designed the study, and analyzed and interpreted data, and drafted manuscript. All authors revised the manuscript critically for important intellectual content.
Funding: WET-HF registry was supported by a grant from the Japan Agency for Medical Research and Development (S.K. 201439013C), a Grant-in-Aid for Scientific Research (T.Y. JPSS KAKENHI, 23591062, 26461088; T.K. 17K09526), a Grant-in-Aid for Young Scientists (Y.S. JPSS KAKENHI, 18K15860), a Grant-in-Aid for Clinical Research from the Japanese Circulation Society (Y.S. 2019), a Grant-in-Aid from the Japanese Ministry of Health, Labor and Welfare (S.K. H29-Refractory Disease-034), a Health Labor Science Research Grant (S.K. 14528506) and Sakakibara Clinical Research Grant for the Promotion of Science (T.Y. 2012 to 2020).
Disclosures: The authors stated that no such relationships exist, and provided the following details: Dr. Shiraishi is affiliated with an endowed department by Nippon Shinyaku Co., Ltd., Medtronic Japan Co., Ltd., and BIOTRONIK JAPAN Inc., and received research grants from the SECOM Science and Technology Foundation and the Uehara Memorial Foundation and honoraria from Otsuka Pharmaceuticals Co., Ltd. and Ono Pharmaceuticals Co., Ltd.; and Dr. Kohsaka received an unrestricted research grant from the Department of Cardiology, Keio University School of Medicine, Bayer Pharmaceuticals Co., Ltd., Daiichi Sankyo Co., Ltd., and Novartis Pharma Co., Ltd.. The remaining authors have no conflicts of interest to disclose. There are no patents, products in development, or marketed products to declare.
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