Age, gender, comorbidities
|
Clinical presentation
|
Laboratory results
|
Microbiology
results
|
Imaging results
|
Pharmacological
treatment
|
outcome
|
Patient 1
female
6 years
Caucasian
no comorbidities
|
7 days>39°C, conjunctivitis;
rash,
pharyngitis,
strawberry tounge, lymphadenopathy, vomiting
|
CRP 85.9 mg/L;
PCT 0.07ng/ml;
ALT 12U/l;AST 14U/l;albumin 345g/L;
platelets 655×10⁹/l;
lympocytes 1.06x10⁹/l; neutrophils 6.36x10⁹/l;
hemoglobin 11.9g/l
|
Blod culture sterile
Influenza PCR negative
SARS-CoV-2 IgA negative,
SARS-CoV-2 IgG negative,
EBV IgG negative
EBV IgM negative
|
No abnormalities on chest x-ray and abdominal ultrasound
|
cefuroxime
|
Resolution of symptoms,
no abnormailites on echo on 2 and 6 weeks
|
Patient 2
female
16 years
Caucasian
no comorbidities
|
7 days 39°C, mialgia, headache, conjunstivitis, lymphadenopathy, pharyngitis, strawberry tounge, haemorrhagic rash, peripheral oedema, pruritus
|
CRP 336 mg/L;
PCT 3.96ng/ml;
NT-proBNP 492pg/ml; ALT 141U/l;
AST 216U/l;
albumin 34 g/L;
Ferritin 6690μg/L;
D-dimers 10 mg/L;
troponin 16 ng/L;
platelets 199×10⁹/l;
lympocytes 4.94x 10⁹/l; neutrophils 10.0x10⁹/l; hemoglobin 12.7g/l
|
Blod culture sterile
Influenza PCR negative
SARS-CoV-2 PCR negative,
SARS-CoV-2 IgA negative,
SARS-CoV-2 IgG negative,
EBV IgG positive
EBV IgM negative
|
Bilateral basal
lung consolidations, pleural
effusions
|
ceftriaxone, clindamycin
|
Resolution of symptoms,
no abnormailites on echo on 2 weeks
|
Patient 3
male
2 years
Caucasian
no comorbidities
|
7 days >39°C, irritability, conjunstivitis, lymphadenopathy, cracked lips, pharyngitis, strawberry tounge, rash,
peripheral oedema, diarrhoea
|
CRP 56 mg/L;
PCT0.22ng/ml;
NT-proBNP 143pg/ml; ALT 43U/l;
AST 28U/l;
albumin 41 g/L;
platelets 678 ×10⁹/l;
lympocytes 4.94x 10⁹/l; neutrophils 9.2x10⁹/l; hemoglobin 10.4g/l
|
Blod culture sterile
Influenza PCR negative
SARS-CoV-2 IgA negative,
SARS-CoV-2 IgG negative,
EBV IgG negative
EBV IgM negative
|
No abnormalities on chest x-ray and abdominal ultrasound
|
cefuroxime,
IVIG,
Aspirin
|
Good response,
no abnormailites on echo on 2 a nd 6 weeks
|
Patient 4
male
3 years
Caucasian
no comorbidities
|
5 days >39°C,
conjunctivitis; haemorrhagic rash, lymphadenopathy, strawberry tounge, cracked lips, periperal oedema, diarrhoea
|
CRP 67.5 mg/L;
PCT 1.19ng/ml;
ALT 244U/l,
AST 161U/l,
albumin 28g/l;
platelets 386x10⁹/l;
lympocytes 2.75x 10⁹/l ;
neutrophils 17.26x10⁹/l; hemoglobin 10.4g/l
|
Blod culture sterile
Influenza PCR negative
SARS-CoV-2 IgA negative,
SARS-CoV-2 IgG negative,
EBV IgG negative
EBV IgM negative
|
Bilateral pneumonia
|
ceftriaxone,
IVIG,
methylprednisolone, aspirin
|
No response to IVIG, good response after steroid treatment,
no abnormailites on echo on 2 weeks
|
Patient 5
female
4.5 years
Caucasian
no comorbidities
|
10days >39°C,
conjunctivitis;
rash, lymphadenopathy, strawberry tounge, cracked lips, periperal oedema
|
CRP 166 mg/L;
PCT 0.05ng/ml;
ALT 17U/l;
AST 34U/l;
albumin 28g/l;
platelets 610×10⁹/l; lympocytes 5.09x 10⁹/l; neutrophils 4.37x10⁹/l; hemoglobin 8.8g/l
|
Blod culture sterile
Influenza PCR negative
SARS-CoV-2 IgA negative,
SARS-CoV-2 IgG negative,
EBV IgG negative
EBV IgM negative
|
Hepatomegaly, ascites
|
cefuroxime,
IVIG,
aspirin
|
Good response
|
Patient 6
female
15 months
Asian
no comorbidities
|
7days >39°C,
conjunctivitis;
rash, lymphadenopathy, strawberry tounge
|
CRP 67 mg/L;
PCT 0.89ng/ml;
ALT 9U/l;
AST 18U/l;
albumin 33g/l,
platelets 386×10⁹/l; lympocytes 2.75x10⁹/l; neutrophils 17.26x10⁹/l; hemoglobin 10.4g/l
|
Blod culture sterile
Influenza PCR negative
SARS-CoV-2 IgA negative,
SARS-CoV-2 IgG negative,
EBV IgG negative
EBV IgM negative
|
Ascites, pleural
effusion, dilated RCA
|
cefuroxime,
IVIG,
aspirin
|
Good response
|