Table 1: The association between demographics, sleep apnea- and positive airway pressure (PAP) treatment-related characteristics and whether or not a patient was considered adherent (defined as PAP therapy used ≥70% of days for ≥4 hours) estimated using logistic regression analyses. Estimates presented as odds ratio (ORs) and 95% confidence intervals*.
|
Univariate
|
Multivariate
|
Odds Ratio
(95 % CI)
|
p-value
|
Odds Ratio
(95 % CI)
|
p-value
|
Demographics at positive airway pressure (PAP) therapy start date (self-reported)
|
Sex: Male vs. Female
|
1.13
(1.05 – 1.22)
|
0.002
|
1.10
(0.92 – 1.30)
|
0.34
|
↑Height (m), per standard deviation (SD) (11cm)
|
0.99
(0.95 – 1.04)
|
0.80
|
—
|
—
|
↑Weight (kg), per SD (23.4kg)
|
1.15
(1.10 – 1.20)
|
<0.0001
|
—
|
—
|
↑BMI, per SD (7.7kg/m2)
|
1.17
(1.11 – 1.22)
|
<0.0001
|
1.16
(1.05 – 1.29)
|
0.003
|
↑Age (years), per SD (14.3 years)
|
1.33
(1.28 – 1.38)
|
<0.0001
|
1.16
(1.06 – 1.27)
|
0.001
|
Baseline obstructive sleep apnea severity
|
↑AHI, per SD (26.2/hour)
|
1.25
(1.17 – 1.32)
|
<0.0001
|
—
|
—
|
↑RDI, per SD (22.4/hour)
|
1.33
(1.23 – 1.44)
|
<0.0001
|
—
|
—
|
↑Respiratory index: AHI or RDI (if AHI unavailable), per SD (25.7/hour)
|
1.25
(1.18 – 1.32)
|
<0.0001
|
1.075
(0.97 – 1.20)
|
0.18
|
↑Minimum SaO2 (%), per SD (7.8%)
|
0.79
(0.73 – 0.85)
|
<0.0001
|
0.89
(0.80 – 0.99)
|
0.03
|
Type of PAP treatment
|
APAP vs. CPAP
|
0.91
(0.84 – 0.98)
|
0.02
|
0.91
(0.76 – 1.09)
|
0.49
|
Bilevel vs. CPAP
|
1.00
(0.89 – 1.11)
|
0.97
|
1.13
(0.89 – 1.43)
|
0.40
|
*ORs were standardized using the standard deviation of the variable in question.
Apnea-hypopnea index, AHI; auto-titrating positive airway pressure treatment, APAP; body mass index, BMI; confidence interval, CI; continuous positive airway pressure, CPAP; oxygen saturation, SaO2; respiratory disturbance index, RDI; standard deviation, SD
Table 2: The association between demographics, sleep apnea- and positive airway pressure (PAP) treatment-related characteristics and changes in percent of days PAP was used regardless of number of hours per night (left) and number of days PAP was used a minimum of 4 hours per night (right) estimated using linear regression analyses. Estimates presented as beta coefficients and 95% confidence intervals*.
|
Days PAP used >4 hours
|
% Days PAP used for any amount of time
|
|
Multivariate
|
Multivariate
|
Beta
(95 % CI)
|
p-value
|
Beta
(95 % CI)
|
p-value
|
Demographics at positive airway pressure (PAP) therapy start date (self-reported)
|
Sex: Male vs. Female
|
5.2
(-26.3 – 36.7)
|
0.75
|
3.8
(1.3 – 6.2)
|
0.002
|
↑BMI, per SD (7.7kg/m2)
|
19.7
(1.8 – 37.6)
|
0.031
|
2.3
(0.9 – 3.7)
|
0.001
|
↑Age (years), per SD (14.3 years)
|
11.7
(-4.8 – 28.2)
|
0.166
|
3.0
(1.7 – 4.3)
|
<0.0001
|
Baseline obstructive sleep apnea severity
|
↑Respiratory index: AHI or RDI (if AHI unavailable), per SD (25.7/hour)
|
36.1
(17.5 – 54.6)
|
<0.0001
|
2.1
(0.7 – 3.6)
|
0.004
|
↑Minimum SaO2 (%), per SD (7.8%)
|
-29.9
(-48.7 – -11.2)
|
0.002
|
-3.0
(-4.4 – -1.5)
|
<0.0001
|
Type of PAP treatment
|
APAP vs. CPAP
|
-24.5
(-58.2 – 9.2)
|
0.154
|
1.5
(-1.1 – 4.1)
|
0.261
|
Bilevel vs. CPAP
|
-2.9
(-46.5 – 40.6)
|
0.895
|
2.2
(-1.2 – 5.6)
|
0.202
|
*Beta coefficients were standardized using the standard deviation of the variable in question.
Apnea-hypopnea index, AHI; auto-titrating positive airway pressure treatment, APAP; body mass index, BMI; confidence interval, CI; continuous positive airway pressure, CPAP; oxygen saturation, SaO2; respiratory disturbance index, RDI; standard deviation, SD