1 Sparks JA. Rheumatoid Arthritis. Ann Intern Med 2019; 170 (1): C1-16.
2 Smolen JS, Aletaha D. Rheumatoid arthritis therapy reappraisal: strategies, opportunities and challenges. Nat Rev Rheumatol 2015; 11 (5): 276-89.
3 Khan ZA, Tripathi R, Mishra B. Methotrexate: a detailed review on drug delivery and clinical aspects. Expert Opin Drug Deliv 2012; 9 (2): 151-69.
4 Hoes JN, Jacobs JW, Buttgereit F, Bijlsma JW. Current view of glucocorticoid co-therapy with DMARDs in rheumatoid arthritis. Nat Rev Rheumatol 2010; 6 (12): 693-702.
5 Jia Z, Zhao G, Wei X, Kong D, Sun Y, Zhou Y, et al. Structural optimization of HPMA copolymer-based dexamethasone prodrug for improved treatment of inflammatory arthritis. J Control Release 2020; 324: 560-73.
6 Jagdale SC, Deore GK, Chabukswar AR. Development of Microemulsion Based Nabumetone Transdermal Delivery for Treatment of Arthritis. Recent Pat Drug Deliv Formul 2018; 12 (2): 130-49.
7 Yeo J, Lee YM, Lee J, Park D, Kim K, Kim J, et al. Nitric Oxide-Scavenging Nanogel for Treating Rheumatoid Arthritis. Nano Lett 2019; 19 (10): 6716-24.
8 Jia Z, Zhao G, Wei X, Kong D, Sun Y, Zhou Y, et al. Structural optimization of HPMA copolymer-based dexamethasone prodrug for improved treatment of inflammatory arthritis. J Control Release 2020; 324: 560-73.
9 Chejara DR, Mabrouk M, Kumar P, Choonara YE, Kondiah P, Badhe RV, et al. Synthesis and Evaluation of a Sodium Alginate-4-Aminosalicylic Acid Based Microporous Hydrogel for Potential Viscosupplementation for Joint Injuries and Arthritis-Induced Conditions. Mar Drugs 2017; 15 (8).
10 Wang Q, Jiang J, Chen W, Jiang H, Zhang Z, Sun X. Targeted delivery of low-dose dexamethasone using PCL-PEG micelles for effective treatment of rheumatoid arthritis. J Control Release 2016; 230: 64-72.
11 Fish MB, Banka AL, Braunreuther M, Fromen CA, Kelley WJ, Lee J, et al. Deformable microparticles for shuttling nanoparticles to the vascular wall. Sci Adv 2021; 7 (17).
12 Li Y, Chen X, Jin R, Chen L, Dang M, Cao H, et al. Injectable hydrogel with MSNs/microRNA-21-5p delivery enables both immunomodification and enhanced angiogenesis for myocardial infarction therapy in pigs. Sci Adv 2021; 7 (9).
13 Xue C, Sutrisno L, Li M, Zhu W, Fei Y, Liu C, et al. Implantable multifunctional black phosphorus nanoformulation-deposited biodegradable scaffold for combinational photothermal/ chemotherapy and wound healing. Biomaterials 2021; 269: 120623.
14 Zhou X, He X, Shi K, Yuan L, Yang Y, Liu Q, et al. Injectable Thermosensitive Hydrogel Containing Erlotinib-Loaded Hollow Mesoporous Silica Nanoparticles as a Localized Drug Delivery System for NSCLC Therapy. Adv Sci (Weinh) 2020; 7 (23): 2001442.
15 Zhang ZQ, Kim YM, Song SC. Injectable and Quadruple-Functional Hydrogel as an Alternative to Intravenous Delivery for Enhanced Tumor Targeting. ACS Appl Mater Interfaces 2019; 11 (38): 34634-44.
16 Bittner B, Richter W, Schmidt J. Subcutaneous Administration of Biotherapeutics: An Overview of Current Challenges and Opportunities. Biodrugs 2018; 32 (5): 425-40.
17 Zhang H, Han G, Litscher G. Traditional Acupuncture Meets Modern Nanotechnology: Opportunities and Perspectives. Evid Based Complement Alternat Med 2019; 2019: 2146167.
18 Wang R, Yang J, Liu Y, Guan B, Feng Q, Wang Y, et al. The Effect of Acupoint Application of Sinomenine for Rheumatoid Arthritis Measured by Microdialysis and UPLC-MS/MS. Evid Based Complement Alternat Med 2019; 2019: 5135692.
19 Jung SJ, Kook MG, Kim S, Kang KS, Soh KS. Homing of the Stem Cells from the Acupoint ST-36 to the Site of a Spinal Cord Injury: A Preliminary Study. J Acupunct Meridian Stud 2018; 11 (4): 133-36.
20 Wu CC, Chen MF, Lin CC. Absorption of subcutaneous injection of Tc-99m pertechnetate via acupuncture points and non-acupuncture points. Am J Chin Med 1994; 22 (2): 111-18.
21 Fan D, Guo Q, Shen J, Zheng K, Lu C, Zhang G, et al. The Effect of Triptolide in Rheumatoid Arthritis: From Basic Research towards Clinical Translation. Int J Mol Sci 2018; 19 (2).
22 Li P, Yang X, Yang Y, He H, Chou CK, Chen F, et al. Synergistic effect of all-trans-retinal and triptolide encapsulated in an inflammation-targeted nanoparticle on collagen-induced arthritis in mice. J Control Release 2020; 319: 87-103.
23 Ji C, Song F, Huang G, Wang S, Liu H, Liu S, et al. The protective effects of acupoint gel embedding on rats with myocardial ischemia-reperfusion injury. Life Sci 2018; 211: 51-62.
24 Du K, Wang X, Chi L, Li W. Role of Sigma-1 Receptor/p38 MAPK Inhibition in Acupoint Catgut Embedding-Mediated Analgesic Effects in Complete Freund's Adjuvant-Induced Inflammatory Pain. Anesth Analg 2017; 125 (2): 662-69.
25 Hurt JK, Zylka MJ. PAPupuncture has localized and long-lasting antinociceptive effects in mouse models of acute and chronic pain. Mol Pain 2012; 8: 28.
26 Goldman N, Chen M, Fujita T, Xu Q, Peng W, Liu W, et al. Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nat Neurosci 2010; 13 (7): 883-88.
27 Liu L, Hu F, Wang H, Wu X, Eltahan AS, Stanford S, et al. Secreted Protein Acidic and Rich in Cysteine Mediated Biomimetic Delivery of Methotrexate by Albumin-Based Nanomedicines for Rheumatoid Arthritis Therapy. ACS Nano 2019; 13 (5): 5036-48C.
28 Bibian M, Mangelschots J, Gardiner J, Waddington L, Diaz AM, De Geest BG, et al. Rational design of a hexapeptide hydrogelator for controlled-release drug delivery. J Mater Chem B 2015; 3 (5): 759-65.
29 Mann JL, Yu AC, Agmon G, Appel EA. Supramolecular polymeric biomaterials. Biomater Sci 2017; 6 (1): 10-37.
30 Liu Y, Jin J, Xu H, Wang C, Yang Y, Zhao Y, et al. Construction of a pH-responsive, ultralow-dose triptolide nanomedicine for safe rheumatoid arthritis therapy. Acta Biomater 2021; 121: 541-53.
31 Li R, He Y, Zhu Y, Jiang L, Zhang S, Qin J, et al. Route to Rheumatoid Arthritis by Macrophage-Derived Microvesicle-Coated Nanoparticles. Nano Lett 2019; 19 (1): 124-34.
32 Piao X, Zhou J, Xue L. Triptolide decreases rheumatoid arthritis fibroblast-like synoviocyte proliferation, invasion, inflammation and presents a therapeutic effect in collagen-induced arthritis rats via inactivating lncRNA RP11-83J16.1 mediated URI1 and beta-catenin signaling. Int Immunopharmacol 2021; 99: 108010.
33 Chang CM, Hsu YW, Wong HS, Wei JC, Liu X, Liao HT, et al. Characterization of T-Cell Receptor Repertoire in Patients with Rheumatoid Arthritis Receiving Biologic Therapies. Dis Markers 2019; 2019: 2364943.
34 Ren Q, Li M, Deng Y, Lu A, Lu J. Triptolide delivery: Nanotechnology-based carrier systems to enhance efficacy and limit toxicity. Pharmacol Res 2021; 165: 105377.
35 Zhao J, Zhang X, Sun X, Zhao M, Yu C, Lee RJ, et al. Dual-functional lipid polymeric hybrid pH-responsive nanoparticles decorated with cell penetrating peptide and folate for therapy against rheumatoid arthritis. Eur J Pharm Biopharm 2018; 130: 39-47.
36 Yang HY, Jang MS, Li Y, Lee JH, Lee DS. Multifunctional and Redox-Responsive Self-Assembled Magnetic Nanovectors for Protein Delivery and Dual-Modal Imaging. ACS Appl Mater Interfaces 2017; 9 (22): 19184-92.