Biodegradable polymers are gaining attention for applications in drug delivery, tissue engineering, and wound management. Methods for enhancing their potential in these applications include blending non-biodegradable polymers with biodegradable polymers to form blends with unique properties. Herein we report on the effect of non-biodegradable PC on the physical, mechanical, and thermal properties of biodegradable PBS. The PBS/PC blends contained 3, 13, and 27 wt.% PC and were prepared by melt extrusion. The FTIR results revealed apparent compatibility between the two polymers. Even though the blends are compatible, the extent of miscibility depends on how well PC is dispersed in the PBS matrix. According to the SEM micrographs, adding 3 wt.% PC resulted in a miscible polymer blend. However, above this content, agglomeration was observed suggesting possible phase segregation. XRD results revealed peak shifts to higher angles and new peaks forming between