In this coronavirus epidemic period (COVID-19), vaccination is a highly recommended proactive measure. Millions of people are getting vaccination each day, and it isn’t easy to maintain physical records and monitor their health. In addition, most people are not aware of the availability of vaccines in the hospitals and their suitability to get themselves vaccinated. Moreover, post-vaccination effects need careful monitoring. But in today’s situation, frequent physical visits to hospitals may not be possible. If any complications developed post-vaccination may create health ailments. Therefore, there is a need for an appropriate system, mitigating the issues mentioned above in the vaccination process. We design and develop a Machine learning-based tool for early screening and closedloop real-time remote monitoring of coronavirus disease (COVID-19).