1. Adapala RK, Kanugula AK, Paruchuri S, Chilian WM, Thodeti CK: TRPV4 deletion protects heart from myocardial infarction-induced adverse remodeling via modulation of cardiac fibroblast differentiation. Basic Res Cardiol 2020, 115(2):14.
2. Writing Group M, Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, Das SR, de Ferranti S, Despres JP et al: Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation 2016, 133(4):e38-360.
3. Li GM, Zhang CL, Rui RP, Sun B, Guo W: Bioinformatics analysis of common differential genes of coronary artery disease and ischemic cardiomyopathy. Eur Rev Med Pharmacol Sci 2018, 22(11):3553-3569.
4. Chen CH, Wang SS, Wei EI, Chu TY, Hsieh PC: Hyaluronan enhances bone marrow cell therapy for myocardial repair after infarction. Mol Ther 2013, 21(3):670-679.
5. De Marco E, Vacchiano G, Frati P, La Russa R, Santurro A, Scopetti M, Guglielmi G, Fineschi V: Evolution of post-mortem coronary imaging: from selective coronary arteriography to post-mortem CT-angiography and beyond. Radiol Med 2018, 123(5):351-358.
6. Rusnak J, Fastner C, Behnes M, Mashayekhi K, Borggrefe M, Akin I: Biomarkers in Stable Coronary Artery Disease. Curr Pharm Biotechnol 2017, 18(6):456-471.
7. Georgakopoulos-Soares I, Chartoumpekis DV, Kyriazopoulou V, Zaravinos A: EMT Factors and Metabolic Pathways in Cancer. Front Oncol 2020, 10:499.
8. von Gise A, Pu WT: Endocardial and epicardial epithelial to mesenchymal transitions in heart development and disease. Circ Res 2012, 110(12):1628-1645.
9. Zhou B, von Gise A, Ma Q, Hu YW, Pu WT: Genetic fate mapping demonstrates contribution of epicardium-derived cells to the annulus fibrosis of the mammalian heart. Dev Biol 2010, 338(2):251-261.
10. Wilhelmi T, Xu X, Tan X, Hulshoff MS, Maamari S, Sossalla S, Zeisberg M, Zeisberg EM: Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1. Theranostics 2020, 10(9):3905-3924.
11. Souilhol C, Harmsen MC, Evans PC, Krenning G: Endothelial-mesenchymal transition in atherosclerosis. Cardiovasc Res 2018, 114(4):565-577.
12. Khan S, Masood M, Gaur H, Ahmad S, Syed MA: Long non-coding RNA: An immune cells perspective. Life Sci 2021, 271:119152.
13. Uchida S, Dimmeler S: Long noncoding RNAs in cardiovascular diseases. Circ Res 2015, 116(4):737-750.
14. Cunnington MS, Santibanez Koref M, Mayosi BM, Burn J, Keavney B: Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression. PLoS Genet 2010, 6(4):e1000899.
15. Broadbent HM, Peden JF, Lorkowski S, Goel A, Ongen H, Green F, Clarke R, Collins R, Franzosi MG, Tognoni G et al: Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. Hum Mol Genet 2008, 17(6):806-814.
16. Uthman YA, Ibrahim KG, Abubakar B, Bello MB, Malami I, Imam MU, Qusty N, Cruz-Martins N, Batiha GE, Abubakar MB: MALAT1: A promising therapeutic target in metastatic colorectal cancer. Biochem Pharmacol 2021, 190:114657.
17. Xu W, Ding M, Wang B, Cai Y, Guo C, Yuan C: Molecular mechanism of the canonical oncogenic lncRNA MALAT1 in gastric cancer. Curr Med Chem 2021.
18. Cai Q, Gao ML, Huang LS, Chen HS, Pan LH: MALAT1/miRNA-203/Wnt5a: A potential mechanism for regulating coronary artery disease. Int J Cardiol 2021, 329:48.
19. Li L, Wang L, Li H, Han X, Chen S, Yang B, Hu Z, Zhu H, Cai C, Chen J et al: Characterization of LncRNA expression profile and identification of novel LncRNA biomarkers to diagnose coronary artery disease. Atherosclerosis 2018, 275:359-367.
20. Derrien T, Johnson R, Bussotti G, Tanzer A, Djebali S, Tilgner H, Guernec G, Martin D, Merkel A, Knowles DG et al: The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res 2012, 22(9):1775-1789.
21. Newman AM, Liu CL, Green MR, Gentles AJ, Feng W, Xu Y, Hoang CD, Diehn M, Alizadeh AA: Robust enumeration of cell subsets from tissue expression profiles. Nat Methods 2015, 12(5):453-457.
22. Yi M, Nissley DV, McCormick F, Stephens RM: ssGSEA score-based Ras dependency indexes derived from gene expression data reveal potential Ras addiction mechanisms with possible clinical implications. Sci Rep 2020, 10(1):10258.
23. Finotello F, Mayer C, Plattner C, Laschober G, Rieder D, Hackl H, Krogsdam A, Loncova Z, Posch W, Wilflingseder D et al: Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data. Genome Med 2019, 11(1):34.
24. Freshour SL, Kiwala S, Cotto KC, Coffman AC, McMichael JF, Song JJ, Griffith M, Griffith OL, Wagner AH: Integration of the Drug-Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts. Nucleic Acids Res 2021, 49(D1):D1144-D1151.
25. Cao Z, Pan X, Yang Y, Huang Y, Shen HB: The lncLocator: a subcellular localization predictor for long non-coding RNAs based on a stacked ensemble classifier. Bioinformatics 2018, 34(13):2185-2194.
26. Chen LL: Linking Long Noncoding RNA Localization and Function. Trends Biochem Sci 2016, 41(9):761-772.
27. Liu X, Wang Y, Liu F, Zhang M, Song H, Zhou B, Lo CW, Tong S, Hu Z, Zhang Z: Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling. Sci Signal 2018, 11(519).
28. Dong WQ, Chao M, Lu QH, Chai WL, Zhang W, Chen XY, Liang ES, Wang LB, Tian HL, Chen YG et al: Prohibitin overexpression improves myocardial function in diabetic cardiomyopathy. Oncotarget 2016, 7(1):66-80.
29. Xu Z, Jia K, Wang H, Gao F, Zhao S, Li F, Hao J: METTL14-regulated PI3K/Akt signaling pathway via PTEN affects HDAC5-mediated epithelial-mesenchymal transition of renal tubular cells in diabetic kidney disease. Cell Death Dis 2021, 12(1):32.
30. Jing R, Zhong QQ, Long TY, Pan W, Qian ZX: Downregulated miRNA-26a-5p induces the apoptosis of endothelial cells in coronary heart disease by inhibiting PI3K/AKT pathway. Eur Rev Med Pharmacol Sci 2019, 23(11):4940-4947.
31. Xing X, Guo S, Zhang G, Liu Y, Bi S, Wang X, Lu Q: miR-26a-5p protects against myocardial ischemia/reperfusion injury by regulating the PTEN/PI3K/AKT signaling pathway. Braz J Med Biol Res 2020, 53(2):e9106.
32. Li X, Sun S, Chen D, Yuan T, Chen Y, Wang D, Fang L, Lu Y, Du G: Puerarin attenuates the endothelial-mesenchymal transition induced by oxidative stress in human coronary artery endothelial cells through PI3K/AKT pathway. Eur J Pharmacol 2020, 886:173472.
33. Guan BF, Dai XF, Huang QB, Zhao D, Shi JL, Chen C, Zhu Y, Ai F: Icariside II ameliorates myocardial ischemia and reperfusion injury by attenuating inflammation and apoptosis through the regulation of the PI3K/AKT signaling pathway. Mol Med Rep 2020, 22(4):3151-3160.
34. Ju X, Sun Y, Zhang F, Wei X, Wang Z, He X: Long Non-Coding RNA LINC02747 Promotes the Proliferation of Clear Cell Renal Cell Carcinoma by Inhibiting miR-608 and Activating TFE3. Front Oncol 2020, 10:573789.
35. Gu W, Wen D, Lu H, Zhang A, Wang H, Du J, Zeng L, Jiang J: MiR-608 Exerts Anti-inflammatory Effects by Targeting ELANE in Monocytes. J Clin Immunol 2020, 40(1):147-157.
36. Gao S, Liu W, Zhuo X, Wang L, Wang G, Sun T, Zhao Z, Liu J, Tian Y, Zhou J et al: The activation of mTOR is required for monocyte pro-inflammatory response in patients with coronary artery disease. Clin Sci (Lond) 2015, 128(8):517-526.
37. Tabaei S, Motallebnezhad M, Tabaee SS: Vitamin D Receptor (VDR) Gene Polymorphisms and Risk of Coronary Artery Disease (CAD): Systematic Review and Meta-analysis. Biochem Genet 2021, 59(4):813-836.
38. Moradi N, Fadaei R, Ahmadi R, Mohammad MH, Shahmohamadnejad S, Tavakoli-Yaraki M, Aghajani H, Fallah S: Role of serum MMP-9 levels and vitamin D receptor polymorphisms in the susceptibility to coronary artery disease: An association study in Iranian population. Gene 2017, 628:295-300.
39. Bakke D, Sun J: Ancient Nuclear Receptor VDR With New Functions: Microbiome and Inflammation. Inflamm Bowel Dis 2018, 24(6):1149-1154.
40. Long P, Wang Q, Zhang Y, Zhu X, Yu K, Jiang H, Liu X, Zhou M, Yuan Y, Liu K et al: Profile of copper-associated DNA methylation and its association with incident acute coronary syndrome. Clin Epigenetics 2021, 13(1):19.
41. Gomez-Velazquez M, Badia-Careaga C, Lechuga-Vieco AV, Nieto-Arellano R, Tena JJ, Rollan I, Alvarez A, Torroja C, Caceres EF, Roy AR et al: CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart. PLoS Genet 2017, 13(8):e1006985.
42. Zeng Z, Huang N, Zhang Y, Wang Y, Su Y, Zhang H, An Y: CTCF inhibits endoplasmic reticulum stress and apoptosis in cardiomyocytes by upregulating RYR2 via inhibiting S100A1. Life Sci 2020, 242:117158.
43. Antony-Debre I, Bluteau D, Itzykson R, Baccini V, Renneville A, Boehlen F, Morabito M, Droin N, Deswarte C, Chang Y et al: MYH10 protein expression in platelets as a biomarker of RUNX1 and FLI1 alterations. Blood 2012, 120(13):2719-2722.
44. Jiang YX, Yang SW, Li PA, Luo X, Li ZY, Hao YX, Yu PW: The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms. Oncogene 2017, 36(9):1256-1264.
45. Dounousi E, Duni A, Naka KK, Vartholomatos G, Zoccali C: The Innate Immune System and Cardiovascular Disease in ESKD: Monocytes and Natural Killer Cells. Curr Vasc Pharmacol 2021, 19(1):63-76.
46. Yang Y, Xu X: Identification of key genes in coronary artery disease: an integrative approach based on weighted gene co-expression network analysis and their correlation with immune infiltration. Aging (Albany NY) 2021, 13.
47. Jabir NR, Firoz CK, Ahmed F, Kamal MA, Hindawi S, Damanhouri GA, Almehdar HA, Tabrez S: Reduction in CD16/CD56 and CD16/CD3/CD56 Natural Killer Cells in Coronary Artery Disease. Immunol Invest 2017, 46(5):526-535.
48. Yan W, Zhou L, Wen S, Duan Q, Huang F, Tang Y, Liu X, Chai Y, Wang L: Differential loss of natural killer cell activity in patients with acute myocardial infarction and stable angina pectoris. Int J Clin Exp Pathol 2015, 8(11):14667-14675.
49. van Duijn J, Kuiper J, Slutter B: The many faces of CD8+ T cells in atherosclerosis. Curr Opin Lipidol 2018, 29(5):411-416.
50. Ong S, Rose NR, Cihakova D: Natural killer cells in inflammatory heart disease. Clin Immunol 2017, 175:26-33.
51. Guttman M, Rinn JL: Modular regulatory principles of large non-coding RNAs. Nature 2012, 482(7385):339-346.
52. Peng Z, Zhang C, Duan C: Functions and mechanisms of long noncoding RNAs in lung cancer. Onco Targets Ther 2016, 9:4411-4424.
53. Hussen BM, Shoorei H, Mohaqiq M, Dinger ME, Hidayat HJ, Taheri M, Ghafouri-Fard S: The Impact of Non-coding RNAs in the Epithelial to Mesenchymal Transition. Front Mol Biosci 2021, 8:665199.
54. Heallen T, Zhang M, Wang J, Bonilla-Claudio M, Klysik E, Johnson RL, Martin JF: Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size. Science 2011, 332(6028):458-461.
55. Osoegawa K, Iovannisci DM, Lin B, Parodi C, Schultz K, Shaw GM, Lammer EJ: Identification of novel candidate gene loci and increased sex chromosome aneuploidy among infants with conotruncal heart defects. Am J Med Genet A 2014, 164A(2):397-406.
56. Jackson-Weaver O, Ungvijanpunya N, Yuan Y, Qian J, Gou Y, Wu J, Shen H, Chen Y, Li M, Richard S et al: PRMT1-p53 Pathway Controls Epicardial EMT and Invasion. Cell Rep 2020, 31(10):107739.
57. Cooley BC, Nevado J, Mellad J, Yang D, St Hilaire C, Negro A, Fang F, Chen G, San H, Walts AD et al: TGF-beta signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling. Sci Transl Med 2014, 6(227):227ra234.
58. Cheng SL, Shao JS, Behrmann A, Krchma K, Towler DA: Dkk1 and MSX2-Wnt7b signaling reciprocally regulate the endothelial-mesenchymal transition in aortic endothelial cells. Arterioscler Thromb Vasc Biol 2013, 33(7):1679-1689.
59. Kato H, Fu YY, Zhu J, Wang L, Aafaqi S, Rahkonen O, Slorach C, Traister A, Leung CH, Chiasson D et al: Pulmonary vein stenosis and the pathophysiology of "upstream" pulmonary veins. J Thorac Cardiovasc Surg 2014, 148(1):245-253.
60. Wu X, Du X, Yang Y, Liu X, Liu X, Zhang N, Li Y, Jiang X, Jiang Y, Yang Z: Inhibition of miR-122 reduced atherosclerotic lesion formation by regulating NPAS3-mediated endothelial to mesenchymal transition. Life Sci 2021, 265:118816.
61. Ricciardi M, Zanotto M, Malpeli G, Bassi G, Perbellini O, Chilosi M, Bifari F, Krampera M: Epithelial-to-mesenchymal transition (EMT) induced by inflammatory priming elicits mesenchymal stromal cell-like immune-modulatory properties in cancer cells. Br J Cancer 2015, 112(6):1067-1075.
62. Pioli PD, Dahlem TJ, Weis JJ, Weis JH: Deletion of Snai2 and Snai3 results in impaired physical development compounded by lymphocyte deficiency. PLoS One 2013, 8(7):e69216.
63. Pioli PD, Whiteside SK, Weis JJ, Weis JH: Snai2 and Snai3 transcriptionally regulate cellular fitness and functionality of T cell lineages through distinct gene programs. Immunobiology 2016, 221(5):618-633.
64. Manduteanu I, Simionescu M: Inflammation in atherosclerosis: a cause or a result of vascular disorders? J Cell Mol Med 2012, 16(9):1978-1990.
65. Jabir NR, Tabrez S: Cardiovascular disease management through restrained inflammatory responses. Curr Pharm Des 2016, 22(7):940-946.