1. Akunuru S, Geiger H. Aging, Clonality, and Rejuvenation of Hematopoietic Stem Cells. Trends Mol. Med.2016, 22, 701-712
2. Moehrle BM,Geiger H. Aging of hematopoietic stem cells: DNA damage and mutations? Exp. Hematol.2016, 44, 895-901.
3. de Haan G, Lazare SS. Aging of hematopoietic stem cells.Blood. 2018,1;131(5):479-487
4. Chung SS, Park CY.Aging, hematopoiesis, and the myelodysplastic syndromes.Hematology Am Soc Hematol Educ Program. 2017(1):73-78
5.Ren R, Ocampo A, Liu GH, et al.Regulation of Stem Cell Aging by Metabolism and Epigenetics.Cell Metab. 2017 Sep 5;26(3):460-474.
6.Waterstrat A, Van Zant G.Effects of aging on hematopoietic stem and progenitor cells.Cell Metab. 2017 ,26(3):460-474
7. Warren LA, Rossi DJ.Stem cells and aging in the hematopoietic system.Mech Ageing Dev. 2009 ,130(1-2):46-53.
8.Liran I. Shlush. Age-related clonal hematopoiesis. Blood,2018,131:496-504
9.Lee J, Yoon SR, Choi I, et al. Causes and Mechanisms of Hematopoietic Stem Cell Aging.Int J Mol Sci,2019,20(6):13
10.Sahebi M, Hanafi MM, van Wijnen AJ,et al. Towards understanding pre-mRNA splicing mechanisms and the role of SR proteins.Gene. 2016, 587(2):107-19
11.Lulzim Shkreta, Benoit Chabot.The RNA Splicing Response to DNA Damage. Biomolecules, 2015, 5:2935-2977
12.Pan Q,Shai O,Lee LJ,et al. Deep surveying of alternative splicingcomplexity in the human transcriptome by high-throughput sequencing. Nat Genet. 2008, 40:1413–1415.
13.Wang ET, Sandberg R, Luo S, et al. Alternative isoform regulation in human tissue transcriptomes. Nature,2008, 456:470-476
14.Yoshimoto R,Kaida D,Furuno M,et al.Global analysis of pre-mRNA subcellular localization following splicing inhibition by spliceostatin A. RNA. 2017,23(1): 47–57
15.Mathieu Deschenes, Benoit Chabot.The emerging role of alternative splicing in senescence and aging.Aging Cell, 2017,16, pp918-933
16.Daguenet E, Dujardin G, Valcárcel J.The pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches. EMBO Rep,2015 16(12): 1640-55.
17.Scotti MM, Swanson MS. RNA mis-splicing in disease.Nat Rev Genet., 2016,17(1):19-32
18.Chabot B, Shkreta L.Defective control of pre-messenger RNA splicing in human disease. J Cell Biol, 2016, 212(1):13-27
19.Moehrle BM, Geiger H.Aging of hematopoietic stem cells: DNA damage and mutations? Exp Hematol, 2016, 44(10):895-901
20.Roybal GA,Jurica MS. Spliceostatin A inhibits spliceosome assembly subsequent to prespliceosome formation.Nucleic Acids Res. 2010,38(19):6664-72.
21.Mathieu Deschenes, Benoit Chabot. The emerging role of alternative splicing in senescence and aging. Aging Cel,3017,16, pp918-933
22.Matera AG,Wang Z. A day in the life of the spliceosome. Nat. Rev. Mol. Cell Biol,2014, 15:108-121
23.Wahl MC,Luhrmann R. SnapShot: Spliceosome dynamics II. Cell ,2015, 162(2):456-456
24.Yan C, Wan R, Shi Y.Molecular Mechanisms of pre-mRNA Splicing through Structural Biology of the Spliceosome.Cold Spring Harb Perspect Biol. 2019,11(1). pii: a032409
25.Guil S, Gattoni R, Carrascal M, et al.Roles of hnRNP A1, SR proteins, and p68 helicase in c-H-ras alternative splicing regulation.Mol Cell Biol, 2003,23(8):2927-41.
26.Kędzierska H, Piekiełko-Witkowska A. Splicing factors of SR and hnRNP families as regulators of apoptosis in cancer.Cancer Lett, 2017 ,28;396:53-65
27.Liu YC, Cheng SC. Functional roles of DExD/H-box RNA helicases in Pre-mRNA splicing. J Biomed Sci.,2015,22:54
28.Safaee N, Kozlov G, Noronha AM, et al. Interdomain allostery promotes assembly of the poly(A) mRNA complex with PABP and eIF4G. Mol Cell. 2012,48(3):375-86.
29.Burgess HM, Gray NK. mRNA-specific regulation of translation by poly(A)-binding proteins. Biochem Soc Trans. 2010,38:1517-1522.
30.Gorgoni B, Richardson WA, Burgess HM, et al. Poly(A)-binding proteins are functionally distinct and have essential roles during vertebrate development. Proc Natl Acad Sci USA. 2011,108:7844-7849.
31.Cong Ren,Jin Zhang,Wensheng Yan, et al. RNA-binding Protein PCBP2 Regulates p73 Expression and p73-dependent Antioxidant Defense. J Biol Chem. 2016,291(18): 9629–9637.
32.Nygaard HB, Erson-Omay EZ, Wu X, et al.Whole Exome Sequencing of an Exceptional Longevity Cohort. J Gerontol A Biol Sci Med Sci. 2019,74(9):1386-1390
33. Gencheva M, Kato M, Newo AN, et al.Contribution of DEAH-box protein DHX16 in human pre-mRNA splicing. Biochem J. 2010,429(1):25-32
34. Gencheva M, Lin TY, Wu X, et al. Nuclear retention of unspliced pre-mRNAs by mutant DHX16/hPRP2, a spliceosomal DEAH-box protein.J Biol Chem. 2010,285(46):35624-32.
35. Handschuh L, Wojciechowski P, Kazmierczak M, et al. NPM1 alternative transcripts are upregulated in acute myeloid and lymphoblastic leukemia and their expression level affects patient outcome.J Transl Med. 2018,16(1):232
36.Lian X, Dong Y, Zhao M, Liang Y, Jiang W, Li W, Zhang L.RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. J Cell Biochem. 2019, 25. doi: 10.1002/jcb.28417
37.Kanehisa M, Goto S, Sato Y, et al. Data, information, knowledgeand principle: Back to metabolism in KEGG. Nucleic Acids Res. 2014, 42, D199–D205
38.Szklarczyk D,Franceschini A,Wyder S,Forslund K,Heller D,Huerta-Cepas J, Simonovic M, Roth A, Santos A, Tsafou K, et al. STRING v10: Protein-protein interaction networks, integrated over the tree oflife. Nucleic Acids Res. 2015, 43, D447–D452.