Articleposted 2024-10-30 02:25:42
PKLR-modulating compounds show promising effects for the treatment of hepatocellular carcinoma
Adil Mardinoglu, Woonghee Kim, Han Jin, peipei miao, Mehmet Ozcan, Xinmeng Liao, Mengzhen Li, and 8 more authors
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Articleposted 2024-09-11 14:53:48
Effects of ferulic acid and senkyunolide A on cytochrome P450 isoforms activity in rats in vivo and in vitro
Mengnan Qin, Xuepeng Shi, Lin Wei, Jiahui Sun, Bing Shao, Chunjuan Yang, Qian Li, and 1 more authors
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Articleposted 2024-09-10 12:29:13
Integrating Transcriptomic Data with a Novel Drug Efficacy Prediction Model for TCM Active Compound Discovery
Yingcan Li, Yu Shen, Yezi Cai, Jiahui Gao, Lei Huang, Weinuo Si, Kai Zhou, and 2 more authors
Under Revision
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Articleupdated 2024-09-05 18:38:42
Polarised human alveolar epithelia enable identification of dichloroacetate as an effective drug against respiratory viruses
Paula Martínez de Iturrate, Bruno Hernáez, Patricia de los Santos, Alba García-Gómez, Alonso Sánchez-Cruz, Catalina Hernández-Sánchez, Luis Rivas, and 2 more authors
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Articleposted 2024-09-05 10:01:23
Affinity of Drug Candidates Binding to SARS CoV-2 PLpro Assessed Using a Generalized-ensemble Method
Masashi Muramoto, Simon Hikiri, Suzuka Saito, Xie Qilin, Kota Kasahara, Junichi Higo, Takuya Takahashi
Under Review
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Articleposted 2024-07-12 20:31:37
Characterization of a SARS-CoV-2 Omicron BA.5 direct-contact transmission model in hamsters
Kim Handrejk, Katharina S. Schmitz, Edwin J.B. Veldhuis Kroeze, Laura L. A. van Dijk, Peter van Run, Bart L. Haagmans, Anne Moscona, and 4 more authors
Under Review
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Articleposted 2024-06-21 16:46:12
An evaluation of spirooxindoles as blocking agents of SARS-CoV-2 spike/ACE2 fusion and M pro inhibitory agents: Synthesis, biological evaluation and computational analysis
Albert Enama Ehinak, Maloba M. M. Lobe, Conrad V. Simoben, Ian Tietjen, Donatus B. Eni, Joel Cassel, Joseph M. Salvino, and 4 more authors
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Articleposted 2024-06-11 06:01:29
Carfilzomib Shows Therapeutic Potential for Reduction of Liver Fibrosis by Targeting Hepatic Stellate Cell Activation
Ayana Fujiwara, Keisuke Takemura, Anna Tanaka, Kazumi Iwata, Kikuko Amagase, Atsushi Umemura, Takeshi Okanoue, and 4 more authors
Published
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Articleposted 2024-06-10 07:48:39
Rational Design of Phytovirucide that Inhibits the Nucleocapsid Condensates of Tomato Spotted Wilt Virus
Runjiang Song, Zan ning, Jiao Li, Jiahui Yao, Shang Wu, Jianzhuan Li, Feifei Chen, and 1 more authors
Under Review
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Articleposted 2024-06-06 10:26:48
Analysis of post-market adverse events of ivabradine: a real-world study base on FAERS database
Yonghuo Ye, Yuxing Lai, Yuhao Lin, Xingjian Wang, Shaoli Wang
Under Review
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